Effects of Chitosan Intake on Fecal Excretion of Bisphenol A and Di(2-ethyl)phthalate in Rats

Kohda, Noriyuki; Inoue, Shoichiro; Noda, Toshihiro; Saito, Takao

doi:10.1271/bbb.110856

Cited by 8 publications

(2 citation statements)

References 23 publications

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“…Studies suggest that intake of dietary supplements with either soluble or insoluble fiber can result in decreased accumulation of environmental lipophilic toxins and chemicals in the body tissues and on other hand enhance the excretion of these toxins [34]. Considering these evidences, studies on chitosan, a dietary fiber mainly of marine origin, also provided positive correlation in fecal excretion of fats and environmental toxins like Bisphenol-A [35], Dioxins [36], [37], [38], Phthalates [35] and PCB [38].…”

Section: Dietary Fibrementioning

confidence: 99%

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Review on Chitosan Intake and Enhancement in Fecal Excretion of Endocrine Disruptors

Ponnusamy

Rekha

Rajagopal

et al. 2021

JPRI

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Chitin is most abundantly found non-digestible carbohydrate similar to cellulose. It has gained a lot of interest in last few years due to its wide range of applications. They are used as an alternative, dietary supplement. Chitin on deacetylation forms chitosan, an active component of chitin. The degree of deacetylation and molecular weight are the factors that elucidate varying degree of biological property of chitosan. The ability of chitosan in fat and lipid excretion has obtained keen eye among various researchers. This property of chitosan is made use in enhancing the elimination of various harmful environmental lipophilic xenobiotics. Endocrine disruptors are a group of environmental pollutants causing various hazardous effects in living system. They are highly lipophilic, persistent and can accumulate in various tissues. Thus correlating the ability of chitosan to increase excretion of fats and lipophilic xenobiotics showed a promising positive outcome.

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Section: Dietary Fibrementioning

confidence: 99%

“…A study was designed by Noriyuki Kohda [35] on intake of chitosan and fecal excretion of Diethylphthalates (DEHP) in rats. Similar to Noriyuki et al study on bisphenol-A, the study was employed on twenty four weeks old male Sprague Dawley rats.…”

Section: Phthalatesmentioning

confidence: 99%