Effects of chronic exposure of methomyl on the antioxidant system in liver of Nile tilapia (Oreochromis niloticus)

Effect of polychlorinated biphenyls on oxidation stress in the liver of juvenile GIFT, Oreochromis niloticus

“…This study suggested that although PCBs stimulate adaptive increases in the expression of some antioxidant enzyme genes, they also induce oxidation and the depletion of most of the antioxidant enzyme activities Different superscript letters indicate statistically significant differences. and GSH content because of increases in ROS production (Meng et al, 2014). To conclude, the present study presented hepatic impairment of juvenile GIFT following PCB exposure in the form of significant toxic bioaccumulation, blood congestion, and increased antioxidative enzyme activities and transcripts.…”

“…In addition to frequently used oxidative stress markers (SOD, CAT, and GPx), the GSH-related antioxidant system attempted to protect the liver cells of Oreochromes niloticus from hepatotoxicity (Piner and Üner, 2013), and markers in this system include GST, GR activity, GSH content, and the GSH/GSSG ratio among others. Genetic Improvement of Farmed Tilapia (GIFT), O. niloticus, is sensitive to the stress of pollutants and is an ideal subject for toxicity experiments (Piner and Üner, 2013;Meng et al, 2014). The main purpose of the present study was to investigate the hepatic genotoxicity (transcriptional) and antioxidant enzymatic signature (post-transcriptional) in juvenile freshwater tilapia, O. niloticus, in response to 0.5 or 5 mg/L PCB exposure.…”

Current Approaches to and Future Perspectives on Methomyl Degradation in Contaminated Soil/Water Environments

“…Islamy et al [35] reported that genotoxicity increased as the concentration of methomyl increased (0-10 mg L −1 ). Moreover, prolonged exposure to methomyl at a concentration above 20 mg L −1 can result in injury to testicular tissue [36,37]. Several studies have demonstrated that higher concentrations of methomyl might be responsible for the disruption of the endocrine system and expression of the LHR, StAR, 3β-HSD, and ARα genes in testes and the LHβ gene in the pituitary.…”

Effect of polychlorinated biphenyls on osmoregulatory response and apoptosis in GIFT tilapia, Oreochromis niloticus

“…Our previous study indicated that hepatic antioxidant enzymatic activity significantly increased under methomyl exposure in Oreochromis niloticus, which is an ideal subject for toxicity experiments (Meng et al, 2014). The tropical GIFT tilapia (O. niloticus) is suitable for culture in warm waters, and is very sensitive to aquatic environmental factors (Gabriel et al, 2015).…”