Effects of chronic noise stress on spatial memory of rats in relation to neuronal dendritic alteration and free radical-imbalance in hippocampus and medial prefrontal cortex

Manikandan, S.; Padma, M.; Srikumar, Ramakrishnan; Parthasarathy, Narayanaperumal Jeya; Muthuvel, A.; Devi, Rathinasamy Sheela

doi:10.1016/j.neulet.2006.01.037

Cited by 174 publications

(157 citation statements)

References 47 publications

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“…From the results of the MWM tests presented in this study, we conclude that chronic noise exposure induces adverse effects on LM. Our results are in agreement with those of Manikandan and Cui 12,14) . We also found that the performances of young male rats in the 80 dB exposure group were significantly better than those .…”

Section: Discussionsupporting

confidence: 93%

“…Noise intensity used in the study of effects of noise on functions of the central nervous system has typically ranged from 80-120 dB 14,[22][23][24] . In this study, we chose 80 dB and 100 dB, 4 h per day for 30 days as chronic noise, with reference to previous studies 12,14) and our experimental experience. Noise pollution is a widespread and growing problem in China and the levels used in our study were near to those commonly experienced in China.…”

Section: Discussionmentioning

confidence: 99%

“…Some studies focused on this idea with different animal models, and they have documented the acute and chronic neurotoxic effects of noise stress. Furthermore, a study carried out on animals showed that chronic noise-induced oxidative stress may cause the impairment of memory, and reduce the dendritic count in the hippocampus 12) . In Kim's study, the influence of longterm noise on the memory and neurogenesis in the hippocampus of developing rats was investigated 13) .…”

mentioning

confidence: 99%

“…Although monoamine neurotransmitters play a key role in LM, little attention has been paid to their involvement in the deleterious effects of noise stress. LM is coordinated among different brain regions, especially the hippocampus and the medial prefrontal cortex 12,15,16) . In Ravindran's study, rats were subjected to 100 dB broadband white noise for 15 days, which was found to alter the biogenic amine levels in discrete regions of the rat brain 17) .…”

mentioning

confidence: 99%

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Recovery of Chronic Noise Exposure Induced Spatial Learning and Memory Deficits in Young Male Sprague‐Dawley Rats

Chen

Yan

Jiang

et al. 2011

Journal of Occupational Health

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Objective: Noise has always been an important environmental public health issue for mankind. Although reports exist on hippocampaldependent spatial learning and memory (LM) impairment due to noise, there are only a few studies that have examined the effects of recovery from noise stress on LM impairments. Therefore, the present study investigated the effects of recovery from chronic noise exposure on LM deficits. Materials and Methods: In this study, the detrimental effects of noise stress on young male rats in the Morris water maze (MWM) were investigated at 1, 10, 20, 30, and 40 days after the discontinuation of chronic noise exposure of 80 dB or 100 dB for 4 h per day, for 30 days. The levels of monoamine neurotransmitters in the hippocampus were also evaluated by HPLC-EC at the end of each behavioral test. Results: Statistical analysis revealed that rats in the noise-treated groups failed to reach the same level of performance as the controls in the MWM. Further, the levels of dopamine (DA), norepinephrine (NE) and 5-hydroxytryptamine (5-HT) were significantly decreased in the hippocampus after noise exposure. However, the reduction in monoamine levels and impaired water maze performance recovered over time, so that by 30th day after cessation of noise exposure the 80 dB group showed no performance difference from the controls, and by 40th day, the 100 dB group also showed no performance difference from the control. Conclusion:Our findings suggest that noise impaired LM in young male rats and reduced monoamine neurotransmitters in the hippocampus. However, the noise-induced water maze deficits recovered over time, and the concurrent restoration of hippocampal monoamine neurotransmitter levels suggest that they are involved in LM impairments. (J Occup Health 2011; 53: 157-163)

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Recovery of Chronic Noise Exposure Induced Spatial Learning and Memory Deficits in Young Male Sprague‐Dawley Rats

Chen

Yan

Jiang

et al. 2011

Journal of Occupational Health

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“…Recently, increasing animal and clinical evidence has shown that chronic noise exposure has obvious effects on cognitive impairment, such as declined memory and learning. For example, working memory was impaired after chronic noise stress in rats with reduced dentritic count in the hippocampus and prefrontal cortex [2]. Noise exposure during pregnancy impaired spatial learning ability and decreased neurogenesis in the hippocampus in rat pups [3].…”

Section: Introductionmentioning

confidence: 99%

Protective effect of the orientin on noise-induced cognitive impairments in mice

Wang

Feng

et al. 2016

Behavioural Brain Research

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There is increasing evidence that chronic noise stress impairs cognition and induces oxidative stress in the brain. Recently, orientin, a phenolic compound abundant in some fruits, millet, and herbs, has been shown to have antioxidant properties. This study investigated the potential effects of orientin against chronic noiseinduced cognitive decline and its underlying mechanisms. A moderate-intensity noise exposure model was used to investigate the effects of orientin on behavior and biochemical alterations in mice. After 3 weeks of the noise exposure, the mice were treated with orientin (20 mg/kg and 40 mg/kg, oral gavage) for 3 weeks. The chronic noise exposure impaired the learning and memory in mice in the Morris water maze and step-through tests. The noise exposure also decreased exploration and interest in a novel environment in the open field test. The administration of orientin significantly reversed noise-induced alterations in these behavior tests. Moreover, the orientin treatment significantly improved the noise-induced alteration of serum corticosterone and catecholamine levels and oxidative stress in the hippocampus and prefrontal cortex. Furthermore, the orientin treatment ameliorated the noise-induced decrease in brain-derived neurotrophic factor and synapseassociated proteins (synaptophysin and postsynaptic density protein 95) in the hippocampus and prefrontal cortex. Thus, orientin exerts protective effects on noise-induced cognitive decline in mice, specifically by improving central oxidative stress, neurotransmission, and increases synapse-associated proteins. Therefore, supplementation with orientin-enriched food or fruit could be beneficial as a preventive strategy for chronic noise-induced cognitive decline. Disciplines Medicine and Health Sciences Publication DetailsWang, S., Yu, Y., Feng, Y., Zou, F., Zhang, X., Huang, J., Zhang, Y., Zheng, X., Huang, X., Zhu, Y. & Liu, Y. (2016). Protective effect of the orientin on noise-induced cognitive impairments in mice. Behavioural Brain Research, 296 290-300.

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Chronic Stress and Hippocampus Vulnerability to Functional Changes and Health in the Adult

Conrad

2011

The Handbook of Stress

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Effects of chronic noise stress on spatial memory of rats in relation to neuronal dendritic alteration and free radical-imbalance in hippocampus and medial prefrontal cortex

Cited by 174 publications

References 47 publications

Recovery of Chronic Noise Exposure Induced Spatial Learning and Memory Deficits in Young Male Sprague‐Dawley Rats

Recovery of Chronic Noise Exposure Induced Spatial Learning and Memory Deficits in Young Male Sprague‐Dawley Rats

Protective effect of the orientin on noise-induced cognitive impairments in mice

Chronic Stress and Hippocampus Vulnerability to Functional Changes and Health in the Adult

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