Effects of chronic obesity and weight loss on plasma ghrelin and leptin concentrations in dogs

Plasma Ghrelin Levels in Various Stages of Development of Iron Deficiency Anemia

“…4 In some studies, subjective scores of appetite and food intake have increased in children with IDA after iron therapy. 15,16 Ghrelin stimulates food intake. 1,3,4 In our results, ghrelin levels were decreased in children with IDA.…”

Ghrelin - characterization, regulation of synthesis, release and possible role in reproduction

“…Obesity is another condition associated with a reduced plasma ghrelin content in comparison with the same parameter in normallyweighted or lean individuals (Jeusette et al, 2005). Paradoxically, excessively elevated circulating ghrelin level may actually become the factor stimulating food intake, promoting hyperphagia and adipogenesis, decreasing locomotor activity, hence, potentially leading to weight gain and obesity (DelParigi et al, 2002).…”

“…Further interesting conclusions came from experiments in mice with neutralized ghrelin and ghrelin-defi cient mice, which had diminished weight gain despite a high-fat diet (Wortley et al, 2005). Body weight was proved to be superior to feed intake for ghrelin regulation (Jeusette et al, 2005) and an impaired hormone response to feeding status appeared in obese individuals (Ariyasu et al, 2002). In genetically obese animals, a delayed short-term secretion after feeding was shown, what may be mediated by blood glucose levels (Ariyasu et al, 2002).…”

“…Concurrently, ghrelin secretion resulting from feed intake appears to be differently regulated depending on the age of an individual (Miura et al, 2004). Circulating ghrelin levels were proved to be related to body mass not only at birth, but also later on in life (Kitamura et al, 2003;Jeusette et al, 2005). Apart from that, there are some reports indicating possible relationships between plasma ghrelin levels and body composition, especially fat mass and distribution, as well as between plasma ghrelin levels and fi tness (Fagerberg et al, 2003;Kozakowski et al, 2004;Barazzoni et al, 2005).…”

Can Dynamically Micronized Clinoptilolite Improve the Quality of Life, For Senior Beagle Dogs with Obesity

“…It was founded a significant relationship between the degree of overweight of dogs and the body mass index of their owners [6]. Today obesity is one of the leading health treat in pets and the major cause of death as well as the most prevalent nutritional disorder in small animal practice [7][8][9]. To control and prevent obesity, nutritional and physical activity or settlements have been common factors employed [1].…”