Effects of clove (Caryophyllus aromaticus L.) on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells

Paoli, Severo de; Giani, Tania Santos; Presta, G.; Pereira, Mario José dos Santos; Fonseca, Adenilson de Souza da; Brandão-Neto, José; Medeiros, Aldo da Cunha; Santos-Filho, Sebastião David; Bernardo-Filho, Mário

doi:10.1590/s1516-89132007000600022

Cited by 17 publications

(10 citation statements)

References 28 publications

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“…Eugenol is a phenol found in sassafras, myrrh, and especially in the essential oil of clove. It has wide use, acting as a stomach and aromatic stimulant and an antiseptic, and is also used as an expectorant in bronchitis and as a versatile condiment in perfumery industries [1][2][3]. The search for new antimicrobial agents, from natural sources, is intense due to the crescent resistance of pathogenic microorganisms to synthetic products [4,5].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Clove Essential Oil and Eugenyl Acetate Produced by Enzymatic Esterification

Vanin

Orlando

Piazza

et al. 2014

Appl Biochem Biotechnol

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This work reports the maximization of eugenyl acetate production by esterification of essential oil of clove in a solvent-free system using Novozym 435 as catalyst. The antimicrobial and antioxidant activities of clove essential oil and eugenyl acetate produced were determined. The conditions that maximized eugenyl acetate production were 60 °C, essential oil of clove to acetic anhydride ratio of 1:5, 150 rpm, and 10 wt% of enzyme, with a conversion of 99.87 %. A kinetic study was performed to assess the influence of substrates' molar ratio, enzyme concentration, and temperature on product yield. Results show that an excess of anhydride, enzyme concentration of 5.5 wt%, 50 °C, and essential oil of clove to acetic anhydride ratio of 1:5 afforded nearly a complete conversion after 2 h of reaction. Comparing the antibacterial activity of the essential oil of clove before and after esterification, we observed a decrease in the antimicrobial activity of eugenyl acetate, particularly with regard to minimum inhibitory concentration (MIC). Both eugenyl acetate and clove essential oil were most effective to the gram-negative than gram-positive bacteria group. The results showed a high antioxidant potential for essential oil before and particularly after the esterification reaction thus becoming an option for the formulation of new antioxidant products.

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Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Clove Essential Oil and Eugenyl Acetate Produced by Enzymatic Esterification

Vanin

Orlando

Piazza

et al. 2014

Appl Biochem Biotechnol

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“…Clove (Syzygium aromaticum L. Merrill and Perry) is one of the most valuable spices that have been used from centuries as food preservative and for many medicinal purposes. Flower bud have many medicinal proprieties like antiviral, antimicrobial, antifungal general stimulating, hypertensive aphrodisiac, light stomachic, carminative and anaesthetic (Di Paoli et al, 2007;Politeo et al, 2010;Koba et al, 2011;Machado et al, 2011).…”

Section: Issn: 2319-7706 Volume 10 Number 05 (2021)mentioning

confidence: 99%

Eco-friendly Management of Leaf Spot of Brinjal (Solanum melongena L.) caused by Alternaria spp

Tiwari¹,

T.R.Rohini²

2021

Int.J.Curr.Microbiol.App.Sci

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“…O cravo da índia (Syzygium aromaticum) é uma especiaria pertencente à família Myrtacea originada da Ilha Molucas, localizado na Indonésia (Affonso, Rennó, Slana & Franca, 2012) Diversos estudos fitoquímicos realizados com o cravo da índia mostram uma grande proporção de óleo essencial, chegando até 90%, onde o eugenol é o componente majoritário, seguido pelos compostos trans-cariofileno, acetato de eugenila e a-humuleno (Paoli et al, 2007;Pereira et al, 2008).…”

Section: Introductionunclassified

Estudos In silico sobre as atividades anticancerígenas do Eugenol presente no Cravo Da Índia (Syzygium aromaticum)

Oliveira

Arruda

2021

RSD

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Objetivo: Investigar as propriedades anticancerígenas do eugenol usando métodos In silico. Metodologia: é um artigo original utilizando a metodologia In silico atraves dos softwares PASS (Prediction of activity spectra for substances) online e GUSAR disponíveis de forma gratuita e livre. Resultados: Os resultados do sistema operacional online PASS demonstraram diversas atividades biológicas positiva, tais quais efeito antimutagênico, estimulante de caspase, tratamento pré neoplásico e agonista de apoptose tendo uma probabilidade de atividade (PA) bem superior a 0,700. Tais achados reforçam aos descritos na literatura que evidenciam um potencial antineoplásico devido o componente ter efeitos antioxidante, e estar vinculado a expressão de genes envolvidos na apoptose e inflamação. Tal como efeitos na regulação negativa de Bcl-2, COX-2 e IL-1ß, e ações na regulação positiva de P53, Bax e expressão ativa de Caspase-3, caspase-9 além de induzir a via da apoptose mitocondrial. Já pelo software GUSAR, foi observado a toxicidade, demonstrando que na categoria 4, estão as vias de administração intravenosa, oral, e subcutânea, indicando que é pouco tóxico. Já na categoria 5 enquadra-se a via intraperitoneal é relativamente atóxico. Tal achado ainda é obscuro e possui poucos artigos científicos para o embasamento. Conclusão: O Eugenol possui efeitos favoráveis para o tratamento e prevenção de diversos canceres e células mutagênicas, porém ainda há pouco conhecimento sobre a toxicidade deste componente. Assim, necessita de um maior aprofundamento sobre a temática.

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Effects of clove (Caryophyllus aromaticus L.) on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells

Abstract: Clove (Caryophyllus aromaticus L.) has been used for clinical procedures. Blood constituents labeled with

Cited by 17 publications

References 28 publications

Antimicrobial and Antioxidant Activities of Clove Essential Oil and Eugenyl Acetate Produced by Enzymatic Esterification

Antimicrobial and Antioxidant Activities of Clove Essential Oil and Eugenyl Acetate Produced by Enzymatic Esterification

Eco-friendly Management of Leaf Spot of Brinjal (Solanum melongena L.) caused by Alternaria spp

Estudos In silico sobre as atividades anticancerígenas do Eugenol presente no Cravo Da Índia (Syzygium aromaticum)

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