2021
DOI: 10.1007/s10815-021-02233-x
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Effects of controlled ovarian stimulation on vascular barrier and endothelial glycocalyx: a pilot study

Abstract: Purpose Controlled ovarian stimulation significantly amplifies the number of maturing and ovulated follicles as well as ovarian steroid production. The ovarian hyperstimulation syndrome (OHSS) increases capillary permeability and fluid extravasation. Vascular integrity intensely is regulated by an endothelial glycocalyx (EGX) and we have shown that ovulatory cycles are associated with shedding of EGX components. This study investigates if controlled ovarian stimulation impacts on the integrity of… Show more

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Cited by 3 publications
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“… 127 The effects of COS on endothelial function and integrity remain unclear. 128 , 129 Although changes to vascular function, including arterial stiffness and endothelial function, are predictive of long-term CV risk, 130 , 131 a point that remains unclear is whether the vascular health changes associated with COS are transitory or rather persist long-term. Further studies to address this question are urgently warranted.…”
Section: Cardiovascular Implications Of Art and Cosmentioning
confidence: 99%
“… 127 The effects of COS on endothelial function and integrity remain unclear. 128 , 129 Although changes to vascular function, including arterial stiffness and endothelial function, are predictive of long-term CV risk, 130 , 131 a point that remains unclear is whether the vascular health changes associated with COS are transitory or rather persist long-term. Further studies to address this question are urgently warranted.…”
Section: Cardiovascular Implications Of Art and Cosmentioning
confidence: 99%