Effects of Cryolipolysis on Abdominal Adiposity

Abstract

Cryolipolysis is a noninvasive technique of localized fat reduction. Controlled cold exposure is performed in the selective destruction of fat cells. The aim of this study was to investigate the effects of cryolipolysis on adipocytes elimination through histological and sonographic analyses. This study reports the case of a 46-year-old female patient, with complaint of localized abdominal fat and in the preoperative period of abdominoplasty. The patient was submitted to a single 60-minute application of cryolipolysis, temperature of −5°C, on the hypogastrium area, 5 cm below the umbilicus. To study the effects of this treatment, ultrasound images taken before the session and 7, 15, 30, and 45 days after the therapy were analysed. After the abdominoplasty, parts of the treated and the untreated withdrawn abdominal tissues were evaluated macro- and microscopically. In ultrasound images, as well as in macroscopic and histological analyses, significant adipocytes destruction was detected, with consequent fat layer reduction and integrity of areas that were adjacent to the treated tissue. The presence of fibrosis observed during therapy and acknowledged through performed analyses encourages further studies to clarify such finding.

Effects of contrast cryolipolysis on flank region adiposity: Case study

“…Volunteer 1 received contrast cryolipolysis session on the right side, with initial heating application (40°C for 5 min), followed by a low‐temperature positive cooling (8°C for 30 minutes) and by another heating application (38°C for 10 min) . Then, the left side flank underwent a Conventional cryolipolysis session, which consists of the cooling with negative temperature at −7°C for 60 minutes . Only on the left side flank, upon session end, the volunteer received a vigorous massage in the region for 3 minutes to facilitate blood reperfusion.…”

“…During the research, it was possible to observe changes on the individuals weight, waist circumference, and subcutaneous thickness decrease, with changes in the contour of the treated region. In the data analysis, the total body mass change occurred, but it was not considered a clinical transformation, since the cryolipolysis process is local and does not interfere with this variable and this result corroborates with other studies . It is probable that weight reduction may have interfered with localized fat loss and contributed to a reduction in total body mass.…”

“…Contrast cryolipolysis favors the lipolysis process through adipocyte crystallization, associated with a cellular lysis. This process consists of a complex network of metabolic reactions that reduce the quantity of fat cells, which clinically promotes a reduction in measurements and adipocyte volume …”

“…The volunteers underwent a previous evaluation immediately before and 8 weeks after the cirtometry and the photographs, and before and 11 weeks after the ultrasonography. In the physical therapy evaluation, body mass (kg) and cirtometry (cm) were measured at umbilical scar level, 5 cm above and 5 cm below . All evaluations were performed by a single individual, who was responsible for the photograph, body weight, and perimetry evaluations, before and after the applications.…”

Effects of radiofrequency on adipose tissue: A systematic review with meta‐analysis

“…Ectopic accumulation of adipose tissue or excessive accumulation of adipose tissue in typical or atypical anatomical regions is closely related to an imbalance of the energy balance. This imbalance refers to a higher caloric intake when compared to energy consumption . This imbalance has cardiovascular and metabolic implications, as well as a negative impact on self‐image satisfaction …”