The aim of this study was to determine the effects of diazinon on some haematology indices in rainbow trout. During the four day, 10 rainbow trout were exposed to two different concentration of diazinon, 40% (0.66mg/L) and 80% (1.32mg/L), respectively (LC50=1.65mg/L). The values of erythrocytes (RBC), packed cell volume (PCV) and hemoglobin (Hb) were significantly (P less than 0.05) decreased. Whereas, leukocytes (WBC) value increased significantly (P less than 0.05) and then decreased. The values of mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) were significantly (P less than 0.05) increased with diazinon administration. However, the increase in the mean corpuscular hemoglobin content (MCHC) was statistically insignificant (P>0.05). Lymphocyte decreased significantly (P less than 0.05). Neutrophils increased and then decreased significantly (P less than 0.05). In conclusion, the changes blood parameteres of the fish exposed to diazinon may be related to decreased immune system.