Effects of desflurane on middle ear pressure

Öztürk, Özcan; İlçe, Zekeriya; Demiraran, Yavuz; Iskender, Abdülkadir; Güçlü, Ender; Yıldızbaş, Şahnur

doi:10.1016/j.ijporl.2007.05.022

Cited by 10 publications

(8 citation statements)

References 12 publications

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“…This in turn could have affected arterial pressure, blood oxygenation levels and partial CO 2 pressure in the blood. Furthermore, halogenated inhalants and nitrous oxide have been shown to diffuse into the middle ear (Perreault et al, 1982;Chinn et al, 1997;Doyle and Banks, 2003;Ozturk et al, 2006Ozturk et al, , 2007 which can have resulted in altered middle ear mechanics. We cannot exclude that an altered middle ear status and changes in physiological parameters affected our recordings.…”

Section: Discussionmentioning

confidence: 99%

Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

2010

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Section: Discussionmentioning

confidence: 99%

Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

2010

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“…The effects of several agents on the MEP have been investigated in many studies, using nitrous oxide, halothane, sevoflurane, desflurane, isoflurane, and TIVA anesthesia [ 5 , 6 ]. For example, Acar et al [ 9 ] studied the effects of two different agents on the MEP and found that desflurane increased the intraoperative intratympanic pressure, supporting the findings of our study.…”

Section: Discussionmentioning

confidence: 99%

“…They demonstrated that isoflurane affects the MEP less, depending on the blood partition coefficients. In addition, Ozturk et al studied high-flow desflurane anesthesia and did not recommend its use due to the complications arising from the increase in the MEP values [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…Nitrous oxide has been demonstrated to cause a time-related increase in pressure with accumulation in a closed environment, which is true for the middle ear [ 3 , 4 ]. Most previous investigations of the middle ear pressure (MEP) have been performed with nitrous oxide, halothane, sevoflurane, desflurane, and total intravenous anesthesia (TIVA) with propofol [ 5 , 6 ]. Although there are many benefits of using low-flow anesthesia, such as cost reduction, prevention of environmental pollution, increased humidity of the gases, decreased heat loss, and better preservation of the tracheal and bronchial physiology [ 7 , 8 ]; its effects on MEP have not been sufficiently researched.…”

Section: Introductionmentioning

confidence: 99%

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Effects of Total Intravenous Anesthesia and Low- and High-Flow Anesthesia Implementation on Middle Ear Pressure

Ozcan¹,

Yungul²,

Müderris

et al. 2018

BioMed Research International

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Background The middle ear is an air-filled lacuna in the temporal bone. Inhaled anesthetic agents increase the pressure of this lacuna. Therefore, attention must be paid in choosing not only anesthetic agents but also anesthetic method. Aim This study compared the effects of high-flow total intravenous anesthesia (TIVA) and low- and high-flow desflurane anesthesia on middle ear pressure. Study Design Randomized prospective double-blind study. Methods In this retrospective double-blind study, 90 patients (20–65 years old) scheduled to undergo elective thyroidectomies were divided into three randomized anesthesia groups: high-flow desflurane (Group I), low-flow desflurane (Group II), and high-flow TIVA (propofol, remifentanil) (Group III). The hemodynamic and respiratory parameters and tympanometry were measured before induction (T1), 10 minutes after intubation (T2), 10 minutes before the end of the operation (T3), and 5 (T4), 10 (T5), 15 (T6), and 30 (T7) minutes after the operation. Results No statistically significant differences were found in the age, gender, weight, height, body mass index, surgery duration, and anesthetic duration (p > 0.05). There were no statistically significant differences at T1, T3, T4, T5, T6, and T7 (p > 0.007), but there was a significant difference at T2 (p < 0.001), with Groups II and III having lower pressure than Group I (p < 0.001). Conclusion The high-flow desflurane group had higher postinduction middle ear pressure values. Therefore, low-flow anesthesia and TIVA can be used more safely in middle ear surgeries, provided that a well-equipped anesthetic device and appropriate monitoring conditions are available.

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“…Inhalation anesthetics pass to the middle ear area during anesthesia maintenance and increase MEP [13,14,15]. In a study conducted on the effects of desflurane on MEP in 2007, Ozturk et al [16] found that desflurane significantly increased MEP. Acar et al [5] compared the effects of desflurane and isoflurane and found that isoflurane significantly increased MEP when compared to desflurane.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Effects of Desflurane and Sevoflurane on Middle Ear Pressure: A Randomized Controlled Clinical Trial

Düğer¹,

Doğan

İşbir³

et al. 2013

ORL

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Objective: The aim of the present study was to compare the effects of two inhalation anesthetics, desflurane and sevoflurane, on middle ear pressure. Methods: After we obtained written consent from the patients and the approval from our institutional ethical committee, we included 56 ASA I-II patients aged between 18 and 60 years in this study. They were randomly divided into two groups of 28 patients each. Desflurane 4-6% (Group D) or sevoflurane 1-2% (Group S) were used for anesthesia management in patients. Baseline tympanometry was carried out and recorded before the induction of anesthesia on both ears, and 3 more measurements were done and recorded 5, 15 and 30 min after induction. Results: In both groups, middle ear pressure values were found to be significantly elevated when compared to baseline measurements (p < 0.05). When middle ear pressure was compared between the groups, no difference was found between the values obtained at baseline and at 5 min in Group S, while especially the values obtained at 15 min revealed significantly higher middle ear pressures in Group D. Conclusion: It was observed that the increase in middle ear pressure caused by sevoflurane was significantly lower than that caused by desflurane.

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Effects of desflurane on middle ear pressure

Cited by 10 publications

References 12 publications

Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

Effects of Total Intravenous Anesthesia and Low- and High-Flow Anesthesia Implementation on Middle Ear Pressure

Comparison of the Effects of Desflurane and Sevoflurane on Middle Ear Pressure: A Randomized Controlled Clinical Trial

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