Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

Stronks, H. Christiaan; Aarts, Mark C. J.; Klis, Sjaak F.L.

doi:10.1016/j.heares.2009.10.015

Cited by 33 publications

(47 citation statements)

References 55 publications

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“…Stronks et al (2010) found ABR threshold differences of approximately 10 dB SPL for click stimuli, a much smaller difference than the 27 dB SPL here reported. The Stronks study, however, used guinea pigs which may have been one source of the discrepancy.…”

Section: Discussioncontrasting

confidence: 82%

“…In the present study the isoflurane elevation of click thresholds was only about 14 dB, as opposed to the greater than 27 dB elevation of tone thresholds. Given the spectral splatter of click stimuli, the decreased differential effect of isoflurane in Stronks et al (2010) as well as in the present study, is not surprising. Most studies that use ABR thresholds to characterize hearing loss would employ pure tones in addition to clicks or noise.…”

Section: Discussionsupporting

confidence: 65%

“…Ferber-Viart et al (1998) compared the effect of isoflurane and propofol on otoacoustic emissions, but hearing threshold consequences were not examined. It has also been shown that isoflurane attenuates cochlear evoked responses (Stronks et al, 2010). While informative, these and related studies have not directly compared the threshold impact of isoflurane to that of other anesthetics such as ketamine/xylazine.…”

Section: Introductionmentioning

confidence: 99%

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A comparison of the effects of isoflurane and ketamine anesthesia on auditory brainstem response (ABR) thresholds in rats

Ruebhausen¹,

Brozoski²,

Bauer³

2012

Hearing Research

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Section: Discussioncontrasting

confidence: 82%

Section: Discussionsupporting

confidence: 65%

Section: Introductionmentioning

confidence: 99%

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A comparison of the effects of isoflurane and ketamine anesthesia on auditory brainstem response (ABR) thresholds in rats

Ruebhausen¹,

Brozoski²,

Bauer³

2012

Hearing Research

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“…For example, pretrauma lesions of dorsal cochlear nucleus were recently shown to prevent induction of tinnitus by acoustic trauma (Brozoski et al, 2011). Isoflurane suppresses auditory brainstem response amplitudes (Stronks et al, 2010), suggesting that suppression of activity in dorsal cochlear nucleus neurons by isoflurane could be one mechanism by which isoflurane during trauma prevents tinnitus.…”

Section: Discussionmentioning

confidence: 99%

Isoflurane blocks temporary tinnitus

2012

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“…Stronks et al [11] showed that isoflurane dose-dependently increase the threshold of the auditory compound action potential.…”

Section: Discussionmentioning

confidence: 99%

Effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation

Eftekharian

Amizadeh

Mottaghi

et al. 2014

Eur Arch Otorhinolaryngol

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The purpose of the present study was to evaluate effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation. A prospective clinical study in a single-subject design was conducted in the cochlear implant center of a tertiary care University-based hospital. Sixty-one cochlear-implanted children with bilateral, severe to profound sensory neural hearing loss were enrolled in the study. During the operation electrically evoked compound action potentials (e-ECAP) were measured in two phase of general anesthesia; in deep and in light anesthesia. Thresholds of e-ECAP in these two phases of anesthesia were compared. Thirty-one children received HiRes90k1j prosthesis and 30 children received CI24RE prosthesis. Thresholds difference of electrically evoked compound action potential between light and deep anesthesia in all tested electrodes in either group were statistically significant (P < 0.001). Non-measurable e-ECAP in some electrodes at deep anesthesia was measurable in light phase of anesthesia. Depth of anesthesia can have significant influence on e-ECAP threshold and it is important to reduce the depth of anesthesia to achieve better results.

show abstract

Effects of isoflurane on auditory evoked potentials in the cochlea and brainstem of guinea pigs

Cited by 33 publications

References 55 publications

A comparison of the effects of isoflurane and ketamine anesthesia on auditory brainstem response (ABR) thresholds in rats

A comparison of the effects of isoflurane and ketamine anesthesia on auditory brainstem response (ABR) thresholds in rats

Isoflurane blocks temporary tinnitus

Effect of depth of general anesthesia on the threshold of electrically evoked compound action potential in cochlear implantation

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