Effects of dietary Allium mongolicum Regel polysaccharide on growth, lipopolysaccharide-induced antioxidant responses and immune responses in Channa argus

Li, Mu‐Yang; Zhu, Xin‐Ming; Niu, Xiaotian; Chen, Xiu‐Mei; Tian, Jingkui; Kong, Yuanyuan; Zhang, Dongming; Zhao, Lei; Wang, Guiqin

doi:10.1007/s11033-019-04677-y

Cited by 45 publications

(28 citation statements)

References 38 publications

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“…Moreover, studies have shown that MOA and EOA are It is generally known that rumen microorganisms may isomerize unsaturated fatty acids after the degradation of triglycerides into BCFAs through biological hydrogenation. Moreover, some studies have suggested that feeding with Allium mongolicum Regel polysaccharides [14] and flavonoids [28] promotes the antioxidant status in juvenile northern snakehead fish. Therefore, we hypothesized that the antioxidant bioactive components in Allium mongolicum Regel and its extracts can block the biological hydrogenation of rumen microorganisms and reduce the production of BCFAs.…”

Section: Body Fat Three Bcfas Concentrationsmentioning

confidence: 99%

“…In this context, plant extracts have emerged as alternative growth promoters that can be used in the lamb finishing stages and accepted by consumers hypolipidemic, stimulating the appetite, and replenishing kidney. A recent study reported that dietary polysaccharides from Allium mongolicum Regel may increase the weight gain, specific growth rate, and FCR of Channa argus [14]. However, few studies have focused on the application of Allium mongolicum Regel and its extracts in ruminants.…”

Section: Introductionmentioning

confidence: 99%

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Effect of dietary supplementation with Allium mongolicum Regel extracts on growth performance, carcass characteristics, and the fat color and flavor-related branched-chain fatty acids concentration in ram lambs

Liu

2021

Anim Biosci

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Objective: This study aimed to investigate the effect of dietary supplementation with Allium mongolicum Regel extracts on the growth performance, carcass characteristics, fat color, and concentrations of three branched-chain fatty acids related to flavor in ram lambs. Methods: Sixty 3-month-old, male, small-tailed Han sheep were selected and randomly allocated into four groups in a randomized block design. Four feeding treatments were used: 1) a basal diet without supplementation as the control group (CK); 2) the basal diet supplemented with 10 glamb-1 d-1 Allium mongolicum Regel powder as the AMR group; 3) the basal diet supplemented with 3.4 glamb-1 d-1 Allium mongolicum Regel water extract as the AWE group; and 4) the basal diet supplemented with 2.8 glamb-1 d-1 Allium mongolicum Regel ethanol extract as the AFE group. Results: The results demonstrated that the dry matter intake was lower for the AFE group than that in other groups (p=0.001). The feed conversion ratio was greater for the AFE than that in other groups (p=0.039). Dietary supplementation with Allium mongolicum Regel powder and its extracts decreased the concentrations of 4-methyloctanoic acid (MOA) (p<0.001), 4-ethyloctanoic acid (EOA) (p<0.001), and 4-methylnonanoic acid (MNA) (p=0.044) in perirenal adipose tissue compared to those observed in the CK lambs. Dietary supplementation with Allium mongolicum Regel powder and its extracts decreased the concentrations of MOA (p<0.001) and EOA (p<0.001) in dorsal subcutaneous adipose tissue compared to those in the CK lambs. The concentrations of MOA (p<0.001) and EOA (p=0.002) in omental adipose tissue were significantly affected by treatment, although there was a tendency for lower MNA (p=0.

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Section: Body Fat Three Bcfas Concentrationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of dietary supplementation with Allium mongolicum Regel extracts on growth performance, carcass characteristics, and the fat color and flavor-related branched-chain fatty acids concentration in ram lambs

Liu

2021

Anim Biosci

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“…When an LPS signal is transmitted to cells, inflammatory mediators are highly expressed and chronic inflammation occurs in the body. Li, Zhu, Niu, Chen, et al () suggested that LPS can induce oxidative stress, alter serum biochemical indicators and increase the relative expression of inflammatory cytokine genes in C. argus . Bouraoui et al () showed that LPS results in the expression of proinflammatory cytokines such as interleukin‐1 (IL‐1), interleukin‐6 (IL‐6), interleukin‐8 (IL‐8) and tumour necrosis factor‐α (TNF‐α) involved in various pathological processes.…”

Section: Introductionmentioning

confidence: 99%

Effects of dietary astaxanthin on growth, blood biochemistry, antioxidant, immune and inflammatory response in lipopolysaccharide‐challengedChanna argus

Zhu

Liu

et al. 2020

Aquac Res

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The present study investigated the effects of dietary astaxanthin on the growth, blood biochemical, antioxidant, immune and inflammatory response in lipopolysaccharide‐challenged Channa argus. A total of 0, 50, 100 and 200 mg/kg of astaxanthin were added to the basal die for 56 days. After the feeding experiment, each group was subjected to a lipopolysaccharide challenge (except for the Control group). The results showed that adding astaxanthin to the diet can significantly increase the weight gain and specific growth rate and decrease the feed conversion ratio of C. argus; the highest weight gain, specific growth rate and minimum feed conversion ratio occurred in the 100 mg/kg group. Furthermore, dietary astaxanthin supplementation can alleviate the negative effects of lipopolysaccharides by increasing the levels of alkaline phosphatase, lysozyme, complement 3, complement 4, total serum protein, albumin, globulin, superoxide dismutase, catalase and glutathione peroxidase and decrease the serum cortisol, aspartate aminotransferase, alanine aminotransferase, glutathione peroxidase, and malondialdehyde. Dietary astaxanthin supplementation also can decrease the relative expression of inflammatory genes (nuclear factor κB, interleukin‐1, interleukin‐8 and tumour necrosis factor‐α) in the liver, spleen, kidney and intestine. To summarise, dietary astaxanthin addition can improve the growth performance and attenuate the negative effects of lipopolysaccharide challenge in C. argus. The optimal amount of astaxanthin is 100 mg/kg.

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“…Dose-dependent seaweed supplementation increased the plasma T-AOC as well as the GSH levels, and the CAT and SOD activities in the liver of the Atlantic salmon (Salmo salar) (63). Allium mongolicum Regel polysaccharide supplementation exerted significant protective effects against LPS challenge by preventing alterations in the SOD and GST levels in Channa argus (64). In the present study, RGP-1 treatment significantly enhanced the activities of T-SOD, CAT, and GSH-Px, increased the concentration of T-AOC and GSH, and reduced the concentration of MDA in the hepatopancreas (Figure 4).…”

Section: Discussionmentioning

confidence: 99%

The Effects of Oral Rehmannia glutinosa Polysaccharide Administration on Immune Responses, Antioxidant Activity and Resistance Against Aeromonas hydrophila in the Common Carp, Cyprinus carpio L

et al. 2020

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The effects of the oral administration of Rehmannia glutinosa polysaccharide (RGP-1) on the immunoregulatory properties, antioxidant activity, and resistance against Aeromonas hydrophila in Cyprinus carpio L. were investigated. The purified RGP-1 (250, 500, and 1,000 µg/mL) was co-cultured with the head kidney cells of the common carp. The proliferation and phagocytosis activities of the head kidney cells, and the concentration of nitric oxide (NO) and cytokines in the culture medium were determined. Next, 300 common carps (47.66 ± 0.43 g) were randomly divided into five groups; the two control groups (negative and positive) were administered sterile PBS and the three treatment groups were administered different concentrations of RGP-1 (250, 500, and 1,000 µg/mL) for seven days. Subsequently, the positive and treatment groups were infected with A. hydrophila, and the negative group was administered sterile PBS for 24 h. The concentration of NO, cytokines, lysozyme (LZM), and alkaline phosphatase (AKP) in serum, the total antioxidant capacity (T-AOC), the levels of malonaldehyde (MDA) and glutathione (GSH), and the total activities of superoxide dismutase (T-SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in the hepatopancreas of the common carp were tested. We observed that RGP-1 could significantly enhance the proliferation and phagocytosis activities (P < 0.05), besides inducing the production of NO, pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, IL-12) and anti-inflammatory cytokines (IL-10, TGF-β) (P < 0.05) in vitro. The in vivo experimental results revealed that RGP-1 significantly enhanced NO production, protein levels of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6, IL-12), LZM and AKP activities, and the antioxidant content (T-AOC, SOD, CAT, GSH, GSH-Px, and MDA) compared to that observed in the negative group prior to A. hydrophila infection (P < 0.05). NO, pro-inflammatory cytokines, LZM Feng et al. RGP-1 as Immunostimulant in Commom Carp and AKP activities were significantly lower than that in the positive group after infection (P < 0.05). However, whether infected or not, the expression of anti-inflammatory cytokines (IL-10, TGF-β) increased significantly in the RGP-1-treated groups (P < 0.05). Therefore, the results suggested that RGP-1 could enhance the non-specific immunity, antioxidant activity and anti-A. hydrophila activity of the common carp, and could be used as a safe and effective feed additive in aquaculture.

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Effects of dietary Allium mongolicum Regel polysaccharide on growth, lipopolysaccharide-induced antioxidant responses and immune responses in Channa argus

Cited by 45 publications

References 38 publications

Effect of dietary supplementation with Allium mongolicum Regel extracts on growth performance, carcass characteristics, and the fat color and flavor-related branched-chain fatty acids concentration in ram lambs

Effect of dietary supplementation with Allium mongolicum Regel extracts on growth performance, carcass characteristics, and the fat color and flavor-related branched-chain fatty acids concentration in ram lambs

Effects of dietary astaxanthin on growth, blood biochemistry, antioxidant, immune and inflammatory response in lipopolysaccharide‐challengedChanna argus

The Effects of Oral Rehmannia glutinosa Polysaccharide Administration on Immune Responses, Antioxidant Activity and Resistance Against Aeromonas hydrophila in the Common Carp, Cyprinus carpio L

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