Effects of dietary coated‐oleum cinnamomi supplementation on the immunity and intestinal integrity of broiler chickens

Guo, Shuangshuang; Cheng, Qiang; Li, Yehan; Duan, Rui; Hou, Yongqing; Ding, Biao

doi:10.1111/asj.13094

Cited by 9 publications

(16 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, the Anti G+ and Anti G− bacterial communities were not able to promote the improvement of intestinal villus height and crypt depth, which departs from previous studies’ results. Other studies have shown that the whole long-term feeding of flavomycin can increase villus height [15] or have no effect [24]. The Anti G+ group built in the first 5 days did not change the intestinal shape.…”

Section: Discussionmentioning

confidence: 90%

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

Yang

Dong

et al. 2019

Microorganisms

View full text Add to dashboard Cite

The composition of the bacterial community affects the intestinal health and growth performance of broiler chickens. The main purpose of this study was to explore the effects of flavomycin and colistin sulfate on the resistance to Salmonella typhimurium infection, ileal bacteria and intestinal health. In total, 396 1-day-old broiler chickens were randomly divided into six groups. Two groups were fed each one of the diets—the control diet (CON), the flavomycin at 10 mg/kg diet (AntiG+), and the colistin sulfate at 40 mg/kg diet (AntiG−), for 5 days. Then, one of each of the two groups was challenged with S. typhimurium on the 8th day; these were named CONS, AntiG+S and AntiG−S, respectively. The results showed that S. typhimurium significantly reduced the feed intake and body weight gain, and increased the feed conversion ratio (p < 0.05). It also increased the inflammatory expressions of NF-κB and MyD88 genes (p < 0.05); and reduced the expressions of claudin-1, occludin and mucin-2 (p < 0.05) tight junction genes in the intestines. S. typhimurium significantly reduced ileal bacterial diversity indexes of observed-species, chao1 and Shannon (p < 0.05). Compared with AntiG+S group, AntiG−S group increased the body weight gain of broiler chickens (p < 0.05), reduced the expression of inflammatory genes (p < 0.05) and intestinal permeability to fluorescein isothiocyanate (p < 0.05). AntiG-S group also improved the ileal bacterial diversity indexes of observed-species and Shannon (p < 0.05). There were many significant correlations between intestinal bacteria, intestinal gene expressions and intestinal morphology (p < 0.05). This study indicated that pre-constructed AntiG− bacteria could against a S. typhimurium infection by inhibiting the expressions of intestinal inflammation genes and increasing the diversity of intestinal bacteria.

show abstract

Section: Discussionmentioning

confidence: 90%

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

Yang

Dong

et al. 2019

Microorganisms

View full text Add to dashboard Cite

show abstract

“…Total RNA isolation and quantitative real-time polymerase chain reaction (qRT-PCR) was conducted as described by Guo et al [17]. Briefly, total RNA of hepatic and cardiac samples was isolated using TRIzol Reagent protocol (Invitrogen, Carlsbad, CA, USA).…”

Section: Rna Isolation and Quantitative Real-time Polymerase Chain Rementioning

confidence: 99%

Effects of N-acetylcysteine on the energy status and antioxidant capacity in heart and liver of cold-stressed broilers

Peng

Liao

et al. 2020

Asian-Australas J Anim Sci

Self Cite

View full text Add to dashboard Cite

Objective: Cold stress induces oxidative damage and impairs energy status of broilers. N-acetylcysteine (NAC) exhibits antioxidant properties and modulates energy metabolism of animals. This study was conducted to investigate the effects of NAC on energy status and antioxidant capacity of heart and liver in the cold-stressed broilers. Methods: The experiment consisted of 4 treatments in a 2×2 factorial arrangement with two diets (basal diet or plus 0.1% NAC) and two ambient temperatures (thermoneutral [conventional ambient temperature] or cold stress [10°C±1°C during days 15 to 42]). Results: No ascites were seen in cold-stressed broilers. NAC did not attenuate the impaired growth performance of stressed birds. However, NAC decreased plasma asparagine but increased aspartate levels in cold-stressed birds (p<0.05). NAC reduced hepatic adenosine triphosphate (ATP) but elevated adenosine diphosphate contents in unstressed birds (p< 0.05). The hepatic ratio of adenosine monophosphate (AMP) to ATP was increased in birds fed NAC (p<0.05). NAC decreased plasma malondialdehyde (MDA) level and cardiac total superoxide dismutase (T-SOD) activity in unstressed birds, but increased hepatic activities of T-SOD, catalase and glutathione peroxidase in stressed birds (p<0.05). NAC down-regulated hepatic AMP-activated protein kinase but up-regulated cardiac heme-oxigenase mRNA expression in stressed birds, and decreased expression of hepatic peroxisome proliferatoractivated receptor coactivator-1α as well as hypoxia-inducible factor-1α in liver and heart of birds. Conclusion: Dietary NAC did not affect energy status but enhanced the hepatic antioxidant capacity by increasing the activities of antioxidant enzymes in cold-stressed broilers.

show abstract

“…Moreover, apart from a positive influence on intestinal morphology in some aspects, PFA supplementation was sometimes associated with a decrease in villous height in the supplemented groups 49 , 144 , 145 . Dietary supplementation of chicken broilers with cOCM was associated with improved intestinal integrity manifested by villus development and modulation of the gene expression of TJ proteins and MUC-2, but no improvement in the birdsʼ growth performance was observed 144 . This is consistent with the results of PFA supplementation (commercial phytogenic product Digestarom) obtained by Ahsan et al, where there was no difference among the dietary treatments for growth performance and cecal microbe populations at any phase 12 .…”

Section: Gut Health and The Intestinal Barriermentioning

confidence: 96%

“…The more the epithelium is exposed to various harmful factors, the greater the depth of the crypts. The positive effect of PFAs (a combination of carvacrol, cinnamaldehyde, and Capsicum oleoresin, piperine, genistein and hesperidin, oregano EO, lavender powder, a combination of CUR, carvacrol, thymol and cinnamaldehyde, cOCM) on gut morphology includes reduced CD 15 , 24 , 31 , 35 , 42 , 49 , 144 , 145 , which can be interpreted as limited exposure to various stressors, lesser inflammatory response, and sloughing. The cell turnover is also an energy consuming process and shallow crypts suggest that the bird can spare nutrients for growth 12 .…”

Section: Gut Health and The Intestinal Barriermentioning

confidence: 99%

See 1 more Smart Citation

Phytogenic Compounds for Enhancing Intestinal Barrier Function in Poultry–A Review

et al. 2021

View full text Add to dashboard Cite

After the European Union ban of antibiotic growth promoters, works on different methods of improving gut health have intensified. The poultry industry is struggling with problems that were previously controlled by antibiotic growth promoters, therefore the search for optimal solutions continues. Simultaneously, there is also increasing social pressure to minimize the use of antibiotics and replace them with alternative feed additives. A variety of available alternatives is considered safe by consumers, among which phytogenics play a significant role. However, there are still some limitations that need to be considered. The most questionable are the issues related to bioavailability, metabolism of plant derivatives in birds, and the difficulty of standardizing commercial products. There is still a need for more evidence-based recommendations for the use of phytogenics in livestock. On the other hand, a positive influence of phytogenic compounds on the health of poultry has been previously described by many researchers and practical application of these compounds has auspicious perspectives in poultry production. Supplementation with phytogenic feed additives has been shown to protect birds from various environmental threats leading to impaired intestinal barrier function. Phytogenic feed additives have the potential to improve the overall structure of intestinal mucosa as well as gut barrier function on a molecular level. Recognition of the phytogenicsʼ effect on the components of the intestinal barrier may enable the selection of the most suitable ones to alleviate negative effects of different agents. This review aims to summarize current knowledge of the influence of various phytogenic constituents on the intestinal barrier and health of poultry.

show abstract

Effects of dietary coated‐oleum cinnamomi supplementation on the immunity and intestinal integrity of broiler chickens

Cited by 9 publications

References 40 publications

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

The Effects of Flavomycin and Colistin Sulfate Pre-Treatment on Ileal Bacterial Community Composition, the Response to Salmonella typhimurium and Host Gene Expression in Broiler Chickens

Effects of N-acetylcysteine on the energy status and antioxidant capacity in heart and liver of cold-stressed broilers

Phytogenic Compounds for Enhancing Intestinal Barrier Function in Poultry–A Review

Contact Info

Product

Resources

About