Effects of dietary phytosterols on cholesterol metabolism and atherosclerosis: clinical and experimental evidence

Whittaker, Margaret H.; Frankos, Vasilios H.; Wolterbeek, AndréP.M.; Waalkens-Berendsen, D.H.

doi:10.1016/s0002-9343(00)00588-x

Cited by 14 publications

(11 citation statements)

References 3 publications

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“…Green seaweed species contain 28-isofucocholesterol, cholesterol, 24-methylene-cholesterol and β-sitosterol, whilst brown seaweed contains fucosterol, cholesterol and brassicasterol. Red seaweed contains desmosterol, cholesterol, sitosterol, fucosterol and chalinasterol (Sanchez-Machado et al 2004b;Whittaker et al 2000). The predominant sterol, fucosterol, in the brown seaweed (Laminaria and Undaria) makes up 83-97% of total sterol content (662-2,320 μg g −1 dry weight) and desmosterol in red seaweed (Palmaria and Porphyra), 87-93% of total sterol content (87-337 μg g −1 dry weight).…”

Section: Sterolsmentioning

confidence: 99%

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Bioactive compounds in seaweed: functional food applications and legislation

Holdt

Kraan²

2011

J Appl Phycol

1,638

1,303

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Seaweed is more than the wrap that keeps rice together in sushi. Seaweed biomass is already used for a wide range of other products in food, including stabilising agents. Biorefineries with seaweed as feedstock are attracting worldwide interest and include low-volume, high valueadded products and vice versa. Scientific research on bioactive compounds in seaweed usually takes place on just a few species and compounds. This paper reviews worldwide research on bioactive compounds, mainly of nine genera or species of seaweed, which are also available in European temperate Atlantic waters, i.e. Laminaria sp., Fucus sp., Ascophyllum nodosum, Chondrus crispus, Porphyra sp., Ulva sp., Sargassum sp., Gracilaria sp. and Palmaria palmata. In addition, Undaria pinnatifida is included in this review as this is globally one of the most commonly produced, investigated and available species. Fewer examples of other species abundant worldwide have also been included. This review will supply fundamental information for biorefineries in Atlantic Europe using seaweed as feedstock. Preliminary selection of one or several candidate seaweed species will be possible based on the summary tables and previous research described in this review. This applies either to the choice of high valueadded bioactive products to be exploited in an available species or to the choice of seaweed species when a bioactive compound is desired. Data are presented in tables with species, effect and test organism (if present) with examples of uses to enhance comparisons. In addition, scientific experiments performed on seaweed used as animal feed are presented, and EU, US and Japanese legislation on functional foods is reviewed.

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Section: Sterolsmentioning

confidence: 99%

“…It is reported that plant sterols such as β-sitosterol and fucosterol lead to the decrease of the concentration of cholesterol in the serum in experimental animals and humans (Whittaker et al 2000).…”

Section: Sterolsmentioning

confidence: 99%

Bioactive compounds in seaweed: functional food applications and legislation

Holdt

Kraan²

2011

J Appl Phycol

1,638

1,303

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“…Various species of seaweeds have different sterols, like green seaweeds contain 28 is of ucocholesterol, cholesterol, 24 methylene cholesterol and β-sitosterol while brown seaweeds contain fucosterol, cholesterol and brassicasterol. Red seaweeds contain sterols like desmosterol, cholesterol, sitosterol, fucosterol and chalinasterol [13] [14]. Brown seaweeds (Laminaria and Undaria) contain 83% -97% of fucosterol in total sterol content (662 -2320 μg/g dry weight) and desmosterol of red seaweeds (Palmaria and Porphyra) contain 87% -93% of total sterol content (87 -337 μg/g dry weight).…”

Section: Sterolsmentioning

confidence: 99%

“…However red seaweeds of C. crispus has cholesterol as major sterol. It is reported that plant sterol like β-sitosterol and fucosterol leads to the decrease in the concentration of cholesterol in the serum experimentation in animals and human [14].…”

Section: Sterolsmentioning

confidence: 99%

Bioactive Compounds and Properties of Seaweeds—A Review

Pal¹,

Kamthania²,

Kumar³

2014

OALib

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In last three decades the discovery of metabolite and biological activities from macroalgae has been increased significantly. Many sophisticated modern research tools are available for making of chemical compound but there are still many natural bioactive compounds in the womb of nature which is a mystery, scientist are still working to find out more biologically active compounds. Bioactive substances from seaweeds currently receive the more attention from the pharmaceutical companies for the drug development as well as the researchers. Seaweeds are taking majority of attention from scientists because of its phenomenon bioactive compounds and its properties like anti-viral, anti-tumor, anti-inflammatory and anti-lipedimic and may more properties. This current review described mainly substances like metabolite, properties, and types of seaweeds. Emphasis is given to main metabolite and properties of seaweeds.

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“…It is reported that plant sterols such as β -sitosterol and fucosterol lead to a decreased concentration of cholesterol in the serum in experimental animals and humans (Whittaker et al , 2000).…”

Section: Fat and Fatty Acid Contentmentioning

confidence: 99%