Effects of dietary postbiotic and inulin on growth performance, IGF1 and GHR mRNA expression, faecal microbiota and volatile fatty acids in broilers

Abstract

BackgroundPostbiotics (metabolic products by lactic acid bacteria) and prebiotics have been established as substitute to antibiotics in order to enhance immunity and growth performance in broiler chickens. Nonetheless, insufficient information is available on the effects of postbiotics and prebiotics combination on growth performance, faecal microbiota, pH and volatile fatty acids (VFA), as well as liver insulin like growth factor 1 (IGF1) and growth hormone receptor (GHR) mRNA expressions in broiler chickens. The aim of this experiment was to evaluate the effects of different types of postbiotics with different levels of prebiotic (inulin) on broiler for those parameters.ResultsThe results showed that birds fed T3: (0.3 % RI11 + 0.8 % Inulin), T4: (0.3 % RI11 + 1.0 % Inulin), and T6: (0.3 % RG14+ 1.0 % Inulin) had higher (p < 0.05) final body weight (BW) and total weight gain (WG) than other treatments. Birds fed T3 had lower feed conversion ratio (FCR) which was significantly different from those fed with negative control diet but was similar to other treatments. Postbiotic and inulin increased (p < 0.05) faecal lactic acid bacteria (LAB) and reduced (p < 0.05) Enterobacteriaceae count. Birds fed T4 and T6 had higher faecal acetic acid and propionic acid respectively, and both had higher total VFA and lactic acid bacteria but lower pH and Enterobacteriaceae (ENT) counts compared to other treatments. The liver of birds fed T4 and T6 had higher IGF1 expression compared to other treatments while T6 had higher GHR mRNA expression compared to other treatments.ConclusionsResults indicate that the addition of postbiotics and inulin combinations had beneficial effects on total BW, feed efficiency, mucosa architecture and IGF1 and GHR mRNA expression in broiler chickens.

Dietary Postbiotic Lactobacillus plantarum Improves Serum and Ruminal Antioxidant Activity and Upregulates Hepatic Antioxidant Enzymes and Ruminal Barrier Function in Post-Weaning Lambs

“…The potential of postbiotics is ascribed to the existence of organic acids and antimicrobial compounds like bacteriocins, which possess inhibitory ability against important pathogenic bacteria including Escherichia coli, Listeria monocytogenes, Pediococcus acidilactici, Salmonella typhimurium and Vancomycin-resistant Enterococci (VRE) [1,2]. The dietary supplementation of postbiotics of monogastric like broilers [3][4][5], layer hens [6] and piglets [7,8] were shown to have better performance and were comparable or performed better in comparison to antibiotics. In broilers exposed to heat stress, postbiotics inclusion was shown to alleviate the heat stress effects by the greater growth performance, immune status and gut health [9].…”

Expression and localisation of FSHR, GHR and LHR in different tissues and reproductive organs of female yaks

“…The combination of postbiotics and inulin is beneficial to the expression of the GHR mRNA in broiler chickens, and GHR may be a candidate marker to improve meat production of Japanese Black cattle. Holstein/Japanese Black crosses carried the GHR short allele from their sire [11,16].…”

In vitro effects of inulin and soya bean oligosaccharide on skatole production and the intestinal microbiota in broilers

“…Non-digestible carbohydrates reaching the large intestine are available for microbial fermentation and affect the microbial community (Knudsen, Hedemann, & Laerke, 2012;Rubio et al, 2015). It has been reported that the prebiotic effects of inulin-derived fructans on humans (Salazar et al, 2015) and broilers (Aead, Ghareeb, & Böhm, 2011;Kareem, Loh, Foo, Akit, & Samsudin, 2016;Pruszynska-Oszmalek et al, 2015). Zhou, Kong, Yang, and Yin (2012) found that SBO can improve the gut microbial balance in colon and modulate its metabolism of pigs in vitro.…”