Effects of dietary restriction and protein deprivation on intestinal absorption of protein digestion products in the rat

Abstract

I. Yudkin's (1967) questionnaire on the dietary intake of sugar was given to 41 j businessmen for self-administration.2. The results showed an inverse relationship between sugar intake and relative weight (actual weight as a percentage of expected weight for height and age) and additional evidence suggests a direct relationship between sugar intake and adequate exercise.3. The statement that 'sugar was restricted' was shown to be a €actor of considerable importance affecting the reported level of sugar intake and should be taken into account when comparing different series.4. The positive association between cigarette smoking and mean sugar consumption in this series was due to the low-sugar intake of ex-smokers.5 . In future studies on the role of sucrose in the aetiology of ischaemic disease, both smoking habits and levels of activity should be recorded.

Kinetics of Uptake of L-Leucine and Glycylsarcosine into Normal and Protein Malnourished Young Rat Jejunum

“…= 100-rivation in the immediate postweaning period caused a reduction in maximal mediated transport capacity for both Gly-Sar and leucine when uptake was expressed on the basis of unit length. There was no preservation of peptide uptake relative to amino acid uptake, neither was there an initial increase in absorption as found by Lis et al (7,8) in short-term protein deprivation in adult rats. Furthermore, the reduction observed in this study was not as great as that seen in long-term protein malnutrition in the adult rat (7,8).…”

“…There was no preservation of peptide uptake relative to amino acid uptake, neither was there an initial increase in absorption as found by Lis et al (7,8) in short-term protein deprivation in adult rats. Furthermore, the reduction observed in this study was not as great as that seen in long-term protein malnutrition in the adult rat (7,8). The malnourished young animals had a much greater reduction in gut length compared with the controls than malnourished adult animals in which the reduction in mean intestinal length was only of the order of 5% (7).…”

“…The results have been conflicting, but in general, peptide transport was shown to be less affected than amino acid transport (7,8,9). …”

“…The impact of protein restriction with or without calorie deprivation on amino acid and peptide transport has been investigated in adult man (1) and experimental animals (4,6,7,8,12,15,16,18). The results have been conflicting, but in general, peptide transport was shown to be less affected than amino acid transport (7,8,9).…”

“…metabolism, resulting from a deficiency of isovaleryl-CoA dehydrogenase (7,8). Clinical manifestations include acute attacks of vomiting, acidosis, ataxia, lethargy, and coma (1, 11).…”