Effects of early postoperative enteral nutrition versus usual care on serum albumin, prealbumin, transferrin, time to first flatus and postoperative hospital stay for patients with colorectal cancer: A systematic review and meta-analysis

Yang, Funa; Li, Wei; Hu, Xia; Ding, Youming; Zhou, Xiufang; Li, Dongying

doi:10.1080/10376178.2018.1513809

Cited by 25 publications

(24 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to the results of this work, according to a combined analysis of clinical and laboratory data, enteral nutrition comes to the fore in the relative effectiveness of nutritional support, which is confirmed in a number of the literature [7], [10], [15], [16], [17].…”

Section: Discussionsupporting

confidence: 66%

Nutritional Support for Patients with Diseases of Hepatopancreotoduodenal Zone in the Early After the Operational Period

Kurbanalievich¹,

Vladimirovich²,

Kabildina³

2020

Open Access Maced J Med Sci

View full text Add to dashboard Cite

AIM: Analysis of the effectiveness of nutritive nutrition in cancer patients in the early post-operative period. MATERIALS AND METHODS: The examination included 80 patients with an average age of more than 20 years (men – 35, and women – 4 5). All patients for analysis were divided into two groups: The first, the main-receiving strictly enteral and/or probe nutrition (n = 41), the second, control-isolated parenteral nutrition (n = 39). The dynamics of laboratory examination results was assessed – the level of total blood protein, including albumin, the number of lymphocytes, the values of alanine aminotransferase, aspartate aminotransferase, total blood bilirubin, and serum ferritin. In addition, the duration of the use of enteral and parenteral nutrition, the number of patient days in the intensive care unit, the nutritional status of patients on the subjective global assessment (SGA), and nutritional risk index (NRI) scales were evaluated. RESULTS: Most patients in the control group (n = 31) on the 10–12th days of the post-operative period, according to the SGA and NRI estimates, were in a state of normal nutritional status (n = 8) – in a state of moderate malnutrition. Since the introduction of parenteral nutrition with enteral nutrition (13–15 days), patients with signs of malnutrition have not been identified in this group. The assessment of the dynamics of total blood protein values in patients showed a significant difference between the average values of indicators in the clinical groups throughout the study period (p < 0.05). In the main group, the average content of total blood protein was 62.5 ± 10.0 g/l, in the control group – 57.5 ± 10.1 g/l by 8 days of the post-operative period. The dynamics of specific indicators of the biochemical composition of blood is determined by the methods of surgical intervention, the volume, duration, and nature of the operation. CONCLUSIONS: When carrying out nutritional support in cancer patients operated on for tumors, hepatopancreatoduodenal region, in the early post-operative period, the enteral route to the action of nutrient mixtures may be preferable, provided there is a pronounced intestinal paresis and congestive discharge from the stomach.

show abstract

Section: Discussionsupporting

confidence: 66%

Nutritional Support for Patients with Diseases of Hepatopancreotoduodenal Zone in the Early After the Operational Period

Kurbanalievich¹,

Vladimirovich²,

Kabildina³

2020

Open Access Maced J Med Sci

View full text Add to dashboard Cite

show abstract

“…Zhang et al [23] reported that hyperfibrinogenemia is relevant to advanced tumor stages and poor survival in patients with HCC. PA has a short half-life as a predictor of inflammatory stress and nutritional status [24], making it an effective biomarker for morbidity, mortality and tumor progression [25]. Therefore, fibrinogen to prealbumin ratio (FPR), which combines Fib and PA, has been used to predict clinical efficacy and outcome for several types of human cancers [20,26].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic value of fibrinogen to prealbumin ratio and gamma-glutamyl transpeptidase to platelet ratio in the progression of AFP-negative hepatocellular carcinoma

Huang

et al. 2020

Cancer Cell Int

View full text Add to dashboard Cite

Background: This study aimed to comprehensively assess the diagnostic value of fibrinogen to prealbumin ratio (FPR) and gamma-glutamyl transpeptidase to platelet ratio (GPR) as single markers or in combination in patients with alpha-fetoprotein-negative (AFP-negative) hepatocellular carcinoma (HCC). Methods: A total of 199 healthy controls and 515 AFP-negative patients were enrolled in this study, including 180 HCC inpatients, 151 liver cirrhosis (LC) patients, and 184 chronic hepatitis (CH) cases. Mann-Whitney U or Kruskal-Wallis H test were used to analyze differences between groups in laboratory parameters and clinicopathological features. The diagnostic value of FPR and GPR, alone or in combination, in AFP-negative HCC (AFP-NHCC) patients was determined via a receiver operating characteristic (ROC) curve. Results: The levels of FPR and GPR were gradually increased in the development of AFP-NHCC and positively correlated with the tumor size and Barcelona Clinic Liver Cancer (BCLC) stages. Moreover, GPR was associated with Edmondson-Steiner grades. After univariate logistic regression analysis, FPR and GPR remained independent predictors of adverse outcomes. The combination of FPR and GPR had a good ability to detect AFP-NHCC from the control group (area under curve [AUC] = 0.977), AFP-negative CH (AUC = 0.745), and AFP-negative LC (AUC = 0.666). FPR combined with GPR possessed a larger area (0.943, 0.971) and sensitivity (87.50%, 89.81%) than FPR or GPR alone for differentiating AFP-NHCC with tumor size < 3 cm or at the BCLC-A stage. Conclusions: The pretreatment levels of FPR and GPR played vital roles in the development of AFP-NHCC, especially in patients with early or small AFP-NHCC.

show abstract

“…Increasing evidence supports the idea that nutritional status is significantly associated with long-term outcomes in cancer patients [39], [40]. As a common nutrition marker, blood PA was found to be related to the 5-year survival rate in patients with malignant tumors such as resected esophageal squamous cell carcinoma and hepatocellular carcinoma [41]- [43].…”

Section: Discussionmentioning

confidence: 89%

Short-Term Heart Rate Variability and Blood Biomarkers of Gastric Cancer Prognosis

Wang

Shi

et al. 2020

IEEE Access

View full text Add to dashboard Cite

Inflammation, nutrition, and coagulation play significant roles in cancer prognosis. Autonomic function is also actively involved in tumorigenesis. Previous studies have shown that an elevated C-reactive protein (CRP) level, a serum marker for inflammation, is associated with low heart rate variability (HRV), a common clinical tool for the assessment of autonomic function. It is yet to be investigated whether HRV links to these prognostic factors in cancer patients. Sixty-one patients who were first diagnosed with gastric cancer (GC) were enrolled in this study. Fasting blood samples were collected in the morning seven days before surgery. Blood CRP, prealbumin (PA), and fibrinogen (FIB) were used to assess the inflammation level, nutritional status, and coagulation function respectively. Five-minute resting electrocardiogram (ECG) signals were collected one day before surgical treatment. Short-term HRV time-series were extracted from ECG recordings and were analyzed using commonly-used time-and frequency-domain parameters including standard deviation of normal-to-normal intervals (SDNN), root mean square of successive heartbeat interval differences (RMSSD), very-low-frequency power (VLF), low-frequency power (LF), high-frequency power (HF), total power (TP), LF power in normalized units (LF n.u.), HF power in normalized units (HF n.u.), and ratio of LF to HF (LF/HF). After adjusted for sex, age, body mass index, alcohol consumption, history of diabetes, left ventricular ejection fraction, and hemoglobin levels, our results demonstrated negative associations of HRV with levels of CRP and FIB, while positive associations between HRV and PA level, with effect sizes of as high as 35%-52% standard deviations (SD) changes in CRP, FIB, or PA per 1-SD change in HRV parameters. Therefore, decreased HRV in patients with GC predicts increased burdens of inflammation and coagulation and perturbed nutrition, suggesting that short-term HRV measurement can potentially be a noninvasive biomarker for GC prognosis. INDEX TERMS Gastric cancer, cancer prognosis, heart rate variability, blood biomarker.

show abstract

Effects of early postoperative enteral nutrition versus usual care on serum albumin, prealbumin, transferrin, time to first flatus and postoperative hospital stay for patients with colorectal cancer: A systematic review and meta-analysis

Abstract: EEN can improve nutritional status and promote intestinal function recovery for patients undergoing CRC surgery.

Cited by 25 publications

References 31 publications

Nutritional Support for Patients with Diseases of Hepatopancreotoduodenal Zone in the Early After the Operational Period

Nutritional Support for Patients with Diseases of Hepatopancreotoduodenal Zone in the Early After the Operational Period

Diagnostic value of fibrinogen to prealbumin ratio and gamma-glutamyl transpeptidase to platelet ratio in the progression of AFP-negative hepatocellular carcinoma

Short-Term Heart Rate Variability and Blood Biomarkers of Gastric Cancer Prognosis

Contact Info

Product

Resources

About