Effects of electric discharge surface treatment on the diffusion characteristics of polymers

Plasma Deposition and Treatment for Biomaterial Applications

“…It has been shown that either crosslinking by activated species of inert gases (CASING) or the deposition of a plasma polymerized film can be used to control the diffusion rate of low molecular weight species through a polymer [133]. In two different studies, Colter et al showed that both techniques could significantly reduce the release rate of pilocarpine from a solid drug release device or across a membrane made of hydrogel material [134] and the diffusion of progesterone across a silicone membrane [135].…”

Reduction of Plasticizer Leaching from PVC by Barrier Coatings Deposited Using DBD Processes at Atmospheric Pressure

“…The treatment of the PVC surface with a low pressure plasma leads to a reduction in plasticizer migration higher than 99% 22–29. Also barrier coatings deposited with plasma processes at low pressure lead to similar high barrier effects 30–33. Drawback of low pressure processes are long evacuation times due to the presence of volatile components in the polymer as well as the difficulty to treat polymers continuously.…”

Biomaterial surfaces

“…The low permeability of the dense plasma-polymerized film retards the diffusion of low-molecular-weight compounds from the material. 61 The low perme- ability of plasma-polymerized films can also significantly reduce the rate of release of drugs. This slower rate can increase the lifetime of controIledrelease devices.…”