Effects of Encapsulated Fruit and Vegetable Juice Powder Concentrates on Oxidative Status in Heavy Smokers

Abstract

Intervention with both nutraceutical formulations resulted in improvement in some oxidative alterations attributed to long-term cigarette smoking.

(Poly)phenolic characterization of three food supplements containing 36 different fruits, vegetables and berries

“…Fruit was the main source of flavonoids (35%), while nonalcoholic beverages were the most important sources of phenolic acids (nearly 80%) [50]. Therefore, considering the reported mean values of phenolic intake among different countries, the daily consumption of 6 gelatine capsules -2 of each product (which corresponds to ~ 600 mg of phenolic compounds), which has been used as a dose in the most recent intervention studies applying these supplements [19], would contribute to notably enhance the daily average (poly)phenolic ingestion.…”

Oxidative status in different settings and with different methodological approaches compared by Receiver Operating Characteristic curve analysis

“…b) In the clinical studies considered for the present retrospective analysis [26,[28][29][30], the evaluation of plasma Vitamin E was never carried out as the changing of oxidative status was detected by total and reduced glutathione, cysteine, homocysteine and cysteinylglycine. On the other hand, when Vitamin E was measured [37], in contrast to significant increase in F-MDA and reduction in GSH, no significant changes of both alphaand gamma tocopherol (the two Vit E isoforms) were observed in patients vs controls.…”

“…Exclusion criteria: presence of chronic diseases, cardiovascular episodes within 6 months (coronary artery disease, peripheral or cerebral vascular disease), regular medication, hypertension (defined as systolic or diastolic blood pressure higher than 140 or 100 mm Hg, respectively), impaired renal function, body mass index (BMI b19 or N 25 kg/m 2 ), hyperglycemia, and diabetes mellitus. The healthy controls were all non-smokers (n = 57, M/F 30/27, aged 42.3 ± 11.5 years) [28,30]. b) CRF group.…”

“…Thus, results from previous clinical studies [26,[28][29][30], have been collected and statistically compared for the first time, with the aim to search for the best marker and/or assay and to verify their performance in evidencing oxidative stress.…”

Can nutrition lessen the effects of secondhand smoke exposure among children?

“…In a randomized clinical trial (n = 67) over a 2-month period, daily vitamin C supplementation reduced by about 12 % the measured lipid peroxidation biomarker F2-isoprostanes, an indicator of oxidative stress, in the plasma of non-smokers exposed to SHS (51) . In a recent trial, 101 heavy smokers were randomized to receive three capsules twice daily for 3 months of a fruit-vegetable (FV), fruit-vegetable-berry (FVB), or placebo formulation (52) . The FV and FVB capsules contained 7.5 mg β -carotene each, 234 and 200 mg vitamin C, respectively, and 420 and 600 μ g folate, respectively.…”