Effects of excessive urea on rumen morphology and microbiota in Jianzhou Da'er goat (Capra hircus)

Zhang, Nanchi; Zhang, Hua; Ding, Jiale; Wang, Li; Wei, Yong; Xiang, Yi

doi:10.1016/j.rvsc.2022.10.009

Cited by 2 publications

(1 citation statement)

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“…Both number and size of papillae were in uenced by nutrition intake and the concentrations of SCFA to which they were exposed [8]. Simultaneously, the muscular layer participated in peristalsis of rumen, contributing to the nutrient utilization of ruminant [9]. Previously, Xia et al (2018) reported that with the increase of the dietary crude protein, the acetate, propionate, butyrate and total volatile fatty acid (VFA) concentrations increased in rumen of Holstein bulls [10].…”

Section: Discussionmentioning

confidence: 99%

Effects of dietary crude protein on antioxidant activity, immunocompetence and the structural properties of the rumen in Tibetan sheep (Ovis aries), as determined by transcriptomic analysis

Wu,

Zhang,

et al. 2024

Preprint

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Background: The rumen is a balanced ecosystem harboring a variety of microorganisms and plays an important role in the digestion and absorption of nutrients for ruminant. However, there are few studies on the effects of dietary crude protein on development and function in rumen of Tibetan sheep. The objective of this study was to evaluate the effects of dietary crude protein (CP) on the antioxidant activity, immunocompetence and the structural properties in the rumen of Tibetan sheep. Sixty two-month-old rams with an average weight of 15.40±0.81 Kg were randomly assigned to low-protein diet (10.20% of dry matter, L group) and high-protein diet (11.58% of dry matter, H group). The experiment was conducted over 97 d, including 7 d of adaption to the diets. Results: Hematoxylin & eosin (H&E) results showed that high-protein diet increased papilla length, papilla width and muscular layer in rumen (P < 0.05). Compared with L group, supplementation with 11.58% crude protein increased the activities of T-AOC and SOD significantly (P < 0.05). A total of 612 significant differentially expressed genes (158 up-regulated and 456 down-regulated) were found in response to high-protein diet. Pathways and genes related to fatty acid biosynthesis, nutrition metabolism and muscle development were verified by real-time quantitative polymerase chain reaction. Conclusions: In conclusion, 11.58% crude protein diet had superior papillary development and antioxidant activity of Tibetan sheep, likely through modulating the expression of functional genes.

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Section: Discussionmentioning

confidence: 99%