Effects of external stress on biodegradable orthopedic materials: A review

Li, Xuan; Chu, Chenglin; Chu, Paul K.

doi:10.1016/j.bioactmat.2016.09.002

Cited by 28 publications

(17 citation statements)

References 98 publications

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“…Vücut içerisinde belirli bir süre kaldığında biyolojik olarak parçalanabilen biyoçözünür malzemeler ortopedik cerrahide implantın sürekli varlığının istenmediği hasar görmüş kemik dokularının sabitlenmesi ve rekonstrüksiyonu uygulamalarında kullanılır [87], [88]. Ayrıca biyoemilebilir polimerler ameliyat bölgesine ilaç salınımı için de kullanılabilmektedir.…”

Section: Biyoçözünür Malzemelerunclassified

Biomaterials Used in Orthopedic Implants

Güner¹,

Meran²

2020

Pamukkale J Eng Sci

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Ortopedide biyomalzemeler, travma sonucu kırılan kemiklerin iyileşmesi için sabitleme ya da osteoporoz gibi bir hastalık tarafından hasar gören eklem ya da kemiklerin yerini alması amacıyla kullanılır. Bu malzemelerin çoğunluğunu metaller oluşturmaktadır. Metal olmayan malzemeler ise seramikler, polimerler ve kompozitler olarak üçe ayrılabilir. Bu çalışmada ortopedik implantların üretiminde kullanılan biyomalzemelerin çeşitleri, temel özellikleri, avantaj ve dezavantajları, kullanım alanları ve malzeme seçimine bağlı olarak oluşabilecek sorunlar özetlenmiştir.Orthopedic biomaterials are used in replacement of joints or bones that are damaged by a disease such as osteoporosis or fixation of broken bones. Majority of these materials are metals. Non-metallic materials can be separated into three groups as ceramics, polymers and composites. In this study, the types, fundamental properties, advantages and disadvantages of biomaterials used in the production of orthopedic implants are summarized.

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Section: Biyoçözünür Malzemelerunclassified

Biomaterials Used in Orthopedic Implants

Güner¹,

Meran²

2020

Pamukkale J Eng Sci

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“…There is evidence that the coatings are protective reducing the corrosion rate of the alloy. Also, the CaP compounds in the coatings are favorable for osseointegration initiating the new boneformation [1].…”

Section: -8mentioning

confidence: 99%

“…Such materials can initiate the bone tissue regeneration and be replaced by the newly formed bone. Biocomposites based on bioinert metals or alloys and bioactive calcium phosphate (CaP) coatings are a promising tendency of the new-generation implants development [1].…”

Section: Introductionmentioning

confidence: 99%

Bioactive calcium phosphate coatings on metallic implants

Sedelnikova

Комарова

Sharkeev

et al. 2017

AIP Conference Proceedings

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Biocomposites based on bioinert metals or alloys and bioactive calcium phosphate coatings are a promising tendency of the new-generation implants development. In recent years, the approach of regenerative medicine based on the use of biodegradable biomaterials has been priority direction. Such materials are capable of initiating the bone tissue regeneration and replaced by the newly formed bone. The microarc oxidation (MAO) method allows obtaining the bioactive coatings with a porous structure, special functional properties, and modified by the essential elements. During the last decade, the investigations in the field of the nanostructured biocomposites based on bioinert Ti, Zr, Nb and their alloys with a calcium phosphate coatings deposited by the MAO method have been studied in the Institute of Strength Physics and Materials Science SB RAS, Tomsk. In this article the possibility to produce the bioactive coatings with high antibacterial and osseoconductive properties due to the introduction in the coatings of Zn, Cu, Ag, La, Si elements and wollastonite CaSiO 3 was shown. The high hydrophilic and bioresorbed coatings stimulate the processes of osseointegration of the implant into the bone tissue. A promising direction in the field of the medical material science is a development of the metallic implants with good biomechanical compatibility to the bone, such as Ti-Nb alloys with a low elastic modulus that can be classified as biomaterials of the second generation. Zr and its alloys are promising materials for the dentistry and orthopedic surgery due to their high strength and corrosion resistance. Biodegradable Mg alloys are biomaterials of third generation. Such materials can dissolve with a certain speed in human body and excreted from the body thereby excluding the need for reoperation. This article presents the analysis of the study results of bioactive MAO coatings on Ti, Ti-Nb, Zr-Nb and Mg alloys and their promising medical application.

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“…Mechanical loading also plays a key role in the degradation of magnesium alloys owing to their high stress corrosion sensitivity [ [11] , [12] , [13] ]. Stents are subject to considerable mechanical loadings during the initial deployment and contractions with heartbeats.…”

Section: Introductionmentioning

confidence: 99%

The effect of tensile and fluid shear stress on the in vitro degradation of magnesium alloy for stent applications

Wenxin

et al. 2018

Bioactive Materials

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Magnesium alloys have gained great attention as biodegradable materials for stent applications. Cardiovascular stents are continuously exposed to different types of mechanical loadings simultaneously during service, including tensile, compressive and fluid shear stress. In this study, the in vitro degradation of WE43 wires was investigated under combined effect of tensile loading and fluid shear stress and compared with that experienced an individual loading condition. For the individual mechanical loading treatment, the degradation of magnesium wires was more severely affected by tensile loading than fluid shear stress. Under tensile loading, magnesium wires showed faster increment of corrosion rates, loss of mechanical properties and localized corrosion morphology with the increasing tensile loadings. With the combined stress, smaller variation of the corrosion rates as well as the slower strength degeneration was shown with increasing stress levels, in comparison with the individual treatment of tensile loading. This study could help to understand the effect of complex stress condition on the corrosion of magnesium for the optimization of biodegradable magnesium stents.

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Effects of external stress on biodegradable orthopedic materials: A review

Cited by 28 publications

References 98 publications

Biomaterials Used in Orthopedic Implants

Biomaterials Used in Orthopedic Implants

Bioactive calcium phosphate coatings on metallic implants

The effect of tensile and fluid shear stress on the in vitro degradation of magnesium alloy for stent applications

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