Background: Leukemia is a common cancer among adults with growing prevalence in Iran. This disease affects different aspects of the patient, especially their quality of life. One of the methods to promote hygiene and health and, consequently, quality of life is to empower the family of the patient. Objectives: The effect of family-based empowerment on quality of life in patients with leukemia was studied in this research. Methods: This study was a clinical trial conducted on 46 adult patients with leukemia together with 46 of their family members in 2015. Eligible patients were selected by the available method and randomly placed in two groups of test and control. Tools for gathering data included a demographic questionnaire about the patient and their family member and a specified questionnaire about the quality of life of patients with cancer. Family-based empowerment intervention was held for research samples in the test group based on its quadruple steps (perceived threat, self-efficiency promotion, increase of self-esteem through educational participation, and assessment) in six 90-minute sessions and a second test was conducted a month and half after the intervention. Data were analyzed using the SPSS 20 statistical software. Results: Results of chi-square test reflected that both groups of test and control were similar in terms of demographic information (P > 0.5). Moreover, statistical independent T-test did not show a significant difference in aspects of quality of life in test and control groups before the intervention (P = 0.98) while this test showed a significant difference in both groups after the intervention (P = 0.00), except for the spiritual aspect (p=0.2). Paired T-test indicated a significant increase in aspects of quality of life in the test group after the intervention (p=0.00) while this test reflected a reverse significant difference in general aspect of quality of life in the control group (P = 0.006).
Conclusions:In general, results of this research showed that implementing family-based empowerment pattern has been effective for increasing quality of life in patients with leukemia.