Formaldehyde (FA) is the leading cause of cellular injury and oxidative damage in testis that is one of the main infertility causes. There has been an increasing evidence of herbal remedies use in male infertility treatment. This assay examines the role of Ficus carica (Fc) leaf extracts in sperm parameters and testis of mice intoxicated with FA. Twenty-five adult male mice were randomly divided into control; sham; FA-treated (10 mg/kg twice per day); Fc-treated (200 mg/kg); and FA + Fc-treated groups. Cauda epididymal spermatozoa were analyzed for viability, count, and motility. Testes were weighed and gonadosomatic index (GSI) was calculated. Also, histoarchitecture of seminiferous tubules was assessed in the Haematoxylin and Eosin stained paraffin sections. The findings showed that FA significantly decreased GSI and increased percentage of immotile sperm compared with control group. Disorganized and vacuolated seminiferous epithelium, spermatogenic arrest, and lumen filled with immature germ cells were also observed in the testes. However, Fc leaf extracts improved sperm count, nonprogressive motility of spermatozoa, and GSI in FA-treated testes. Moreover, seminiferous tubule with spermatogenic arrest was rarely seen, indicating that Fc has the positive effects on testis and epididymal sperm parameters exposed with FA.
Littered waste is one of the ubiquitous problems in urban environments. In this study, urban environmental pollution was evaluated for the first time using a new developed index. The findings indicated that cigarette butts with an average 58% are the largest share in the composition of littered waste. In addition, the numbers of littered wastes throughout the study area had a spatial variation. According to clean environment index (CEI), the entire study area was found to be in a moderate status. However, 40% of the study areas were classified in a dirty and extremely dirty status. Comparison of the studied urban land-uses showed that residential land use with CEI equal to 3.38 is interpreted in the clean status, while commercial land use with CEI equal to 15.05 can be classified in the dirty status. The application of CEI has a good capability to assess littered waste; this index can be employed to evaluate the pollution of urban sidewalks and other environments such as beaches.
Background:Nowadays there are more concerns about drug treatment of methamphetamine abusers whereas quality of life (QOL) related supportive psychotherapy is less credited.Objectives:This study aimed to evaluate the effects of family-centered empowerment model on social support and QOL of methamphetamine users and their families.Patients and Methods:This study was a randomized clinical trial; individuals were randomly allocated to three groups: a group for educating methamphetamine users in recovery (95 subjects), a group for educating a family member of methamphetamine users in recovery (95 subjects) and a control group (95 subjects). Data collecting instruments were standard questionnaires of social support and health-related quality of life (HRQOL). Data were analyzed using χ2-test, t-test, paired t-test, Pearson’s correlation and ANOVA.Results:Mean scores of QOL and social support dimensions changed significantly in two intervention groups (P < 0.0001), but didn’t change in the control group (P > 0.05). Also, there was a positive significant relation (P < 0.05) between total social support and all dimensions of QOL for all study groups.Conclusions:Family-centered empowerment model, easily adapted to methamphetamine users and their families, leads to improved social supports and QOL.
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