Cage culture is one of the important methods for intensive culture of tilapia in large water impoundments. But, information related to growth performance of androgen-treated monosex tilapia population during cage culture under the ecological conditions of India is limited. The aim of this study was to compare the growth potential of control, mixed-sex and androgen-treated, monosex tilapia in confined environment of cages. Control and hormone treated fish were stocked separately in mesh cages at a density of 50 fry / m 3 and it was found that the androgen treated monosex fish grew significantly larger than their control mixed-sex counterparts. The monosex population showed a significantly higher weight, length, depth, specific growth rate, daily weight gain, protein efficiency ratio and body protein content than the mixed-sex tilapia population. Thus, culture of hormone treated monosex tilapia in cages can be considered ideal for augmented production of the fish under Indian context.