2014
DOI: 10.3109/08820139.2014.938164
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Effects of Germanium Biotite Supplement on Immune Responses of Vaccinated Mini-pigs to Foot-and-Mouth Disease Virus Challenge

Abstract: Since the outbreaks of foot-and-mouth disease (FMD) in South Korea in 2010-2011, a trivalent vaccine has been used as a routine vaccination. Despite the high efficacy of the trivalent vaccine, low antibody formation was reported in the pig industry and there is considerable concern about the ability of the vaccine to protect against the Andong strain responsible for recent outbreaks in South Korea. To overcome these problems, immunostimulators have been widely used to improve vaccine efficacy in South Korea, a… Show more

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Cited by 6 publications
(4 citation statements)
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“…Mica particles have been continuously developed by several researchers to establish the most effective formulation as feed supplements, and their functions have been explored for application 9 10 11 39 40 . The most recent study by Jung et al .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Mica particles have been continuously developed by several researchers to establish the most effective formulation as feed supplements, and their functions have been explored for application 9 10 11 39 40 . The most recent study by Jung et al .…”
Section: Discussionmentioning
confidence: 99%
“…A recent study has demonstrated that mica exhibits the chemopreventive potential against colorectal cancers 8 . Moreover, mica group has been used as feed supplements to enhance immune activity due to its ability to stimulate immune responses against virus infection 9 10 11 . Recently, Jung et al .…”
mentioning
confidence: 99%
“…Aluminosilicate mineral germanium. -The studies of Germanium Biotite, a supplement containing the aluminosilicate mineral germanium, showed an increase in the immune response to the aphthous fever vaccine (59), an increase in the proliferative response of lymphocytes and lysozyme activity (60) and preventive effects against respiratory disease in cattle (61).…”
Section: Other Germanium-based Compoundsmentioning
confidence: 99%
“…Moreover, MFP has been studied for enhancing immune activity and recently reported in many studies. Administrations of such MFP as feed supplements could be induced to in crease immune responses against viral infections [ 25 - 27 ]. As previously reported that the immune-stimulatory ability of MFP can be efficiently suppressed tumors, most studies have investigated MFP for the anti-tumor and the immune-stimulatory effects in cancer stem cells.…”
Section: Introductionmentioning
confidence: 99%