Effects of Ginger on the Improvement of Asthma 
 [The Evaluation of Its` Treatmental Effects]

Rouhi, Hamid; Ganji, Forouzan; Nasri, Hamid

doi:10.3923/pjn.2006.373.376

Cited by 26 publications

(14 citation statements)

References 8 publications

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“…26 Sample sizes ranged from eight 32 to 334, 13 six studies recruited children 13,14,19,23,24,35 although one of these reported subjects up to age 55 24 (clarification was sought but not received) -and one a mixed age group of 14-20 yrs. 21 Age was not stated in five studies, 17,25,27,37,38 and the remainder recruited adults. Inclusion criteria required demonstration of reversibility in five studies, 18,24,34,35,38 meeting existing diagnostic criteria for asthma in ten studies, 13,14,18,19,23,27,29,30,33,40 or a clinical diagnosis or history of asthma in ten.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…21 Age was not stated in five studies, 17,25,27,37,38 and the remainder recruited adults. Inclusion criteria required demonstration of reversibility in five studies, 18,24,34,35,38 meeting existing diagnostic criteria for asthma in ten studies, 13,14,18,19,23,27,29,30,33,40 or a clinical diagnosis or history of asthma in ten. 17,[20][21][22]25,28,31,32,36,37 Inclusion criteria were not stated in one study.…”

Section: Description Of Studiesmentioning

confidence: 99%

“…13,14,21,[24][25][26]28,30,33,[36][37][38][39][40] Five trials reported subjective assessments. 13,14,20,22,27 …”

Section: Interventions and Outcome Measuresmentioning

confidence: 99%

“…Mean duration of treatment was 8.4 weeks, ranging from three days 32 to 12 months. 29 Primary and secondary outcome measures were reported as follows: forced expiratory volume in one second (FEV 1)/forced vital capacity (FVC) in 14 studies [17][18][19]21,24,[27][28][29][30][32][33][34]39,40 or changes from baseline in four; 22,26,35,38 peak expiratory flow rate (PEFR) in eight 18,19,21,22,24,30,31,39 or changes in PEFR in five; 13,14,22,28,38 vital capacity (VC) in three; 28,35,38 FEF25-75 in one 34 and maximum breathing capacity (MBC) in one. 38 Three studies recorded exacerbation rates, 18,22,39 six changes in medication use, 14,19,28,30,31,37 and 14 recorded symptom scores.…”

Section: Interventions and Outcome Measuresmentioning

confidence: 99%

“…The remainder were RCTs using either parallel groups 14,[18][19][20][21][22][23][24][25][26][27][28][29][30] or a crossover design. [31][32][33][34][35][36][37][38][39][40] All were double blinded except one single blinded study where the colours of study and placebo medicine sachets differed.…”

Section: Description Of Studiesmentioning

confidence: 99%

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Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis

Clark

Arnold

Lasserson

et al. 2010

Primary Care Respiratory Journal

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Aims: To assess the efficacy of herb and plant extracts in the management of asthma.Method: Systematic review and meta-analysis. Multiple database searches identified randomised placebo controlled trials of herbal interventions reporting at least one primary outcome measure. Where possible data were combined for meta-analysis. Primary outcome measures were lung function, exacerbations and reduction in corticosteroid use. Secondary outcome measures were symptoms and symptom scores, use of reliever medications, changes in rates of consultation and adverse effects.Results: Twenty-six studies reporting on 20 herbal preparations were included. Two of six studies reporting change in FEV1 were positive. Little data was available on frequency of exacerbations. For primary outcomes single studies of Boswellia, Mai-Men-Dong-Tang, Pycnogenol, Jia-Wei-Si-Jun-Zi-Tang and Tylophora indica showed potential to improve lung function, and a study of 1.8-Cineol (eucalyptol) showed reduced daily oral steroid dosage.Conclusions: Improvements in symptoms were not strongly supported by objective changes. Most trials were of small sample size, short duration, and poor methodology. Further adequately powered trials are needed to assess these compounds. Such trials should conform to CONSORT guidance, report standardised spirometry, and use validated symptom and severity scores. No recommendations for herbal treatment of asthma can be made from the current evidence.

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Section: Description Of Studiesmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

“…13,14,21,[24][25][26]28,30,33,[36][37][38][39][40] Five trials reported subjective assessments. 13,14,20,22,27 …”

Section: Interventions and Outcome Measuresmentioning

confidence: 99%

Section: Interventions and Outcome Measuresmentioning

confidence: 99%

Section: Description Of Studiesmentioning

confidence: 99%

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Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis

Clark

Arnold

Lasserson

et al. 2010

Primary Care Respiratory Journal

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Herbal interventions for chronic asthma in adults and children

Arnold

Clark²,

Lasserson

et al. 2008

Cochrane Database of Systematic Reviews

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Natural Products Useful in Respiratory Disorders: Focus on Side-Effect Neutralizing Combinations

Khan

Gilani

2015

Phytother. Res.

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This review summarizes literature related to medicinal plants reputed in traditional medical systems for treatment of asthma and coughs. The plants that are pharmacologically investigated for their effectiveness in such conditions, along with respective experimental protocol details, are also discussed. Some of plant origin compounds, which are considered useful as antitussive and antiasthmatic agents, are described as well. Chrysoeriol, a constituent of Aspalathus linearis (Fabaceae) was observed to be selective for relaxant effect in airways (through K channel activation), compared with other smooth muscles. We reported that Hypericum perforatum (Hyperieaceae), Andropogon muricatus (Poaceae), Juniper excelsa (Coniferae) and Nepeta cataria (Lamiaceae) exhibit bronchodilatory action, mediated through combination of Ca antagonist and phospohodiesrase inhibitory mechanisms, which scientifically explains their medicinal use in asthma. Hyocyamus niger (Solanaceae), Artemisia vulgaris (Compositae), Fumaria parviflora (Fumariaceae) and Terminalia bellerica (Combretaceae) caused bronchodilation via dual blockade of muscarinic receptors and Ca influx. Acorus calamus (Araceae), Carum roxburghianum (Apiaceae), Lens culinaris (Fabaceae) and Lepidium sativum (Cruciferae) mediate bronchodilatation through multiple pathways: anticholinergic and inhibition of Ca channels and PDE enzyme(s). In conclusion, this review presents an analysis of different novel combinations of pharmacological activities in medicinal plants with side effect-neutralizing/synergistic potential, setting new trends in the therapeutic options for hyperactive respiratory disorders such as asthma and cough. Copyright © 2015 John Wiley & Sons, Ltd.

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Effects of Ginger on the Improvement of Asthma [The Evaluation of Its` Treatmental Effects]

Cited by 26 publications

References 8 publications

Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis

Herbal interventions for chronic asthma in adults and children: a systematic review and meta-analysis

Herbal interventions for chronic asthma in adults and children

Natural Products Useful in Respiratory Disorders: Focus on Side-Effect Neutralizing Combinations

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