Effects of glutamine on hydrogen peroxide-induced oxidative damage in intestinal epithelial cells of Jian carp (Cyprinus carpio var. Jian)

Effect of dietary isoleucine on the immunity, antioxidant status, tight junctions and microflora in the intestine of juvenile Jian carp (Cyprinus carpio var. Jian)

“…Tissues MDA and PC contents were widely used as biomarkers for oxidative damage of lipids and proteins, respectively [67]. In this study, intestinal MDA and PC contents were the highest for Jian carp fed the Ile-deficient diet, and were reduced with Ile supplement to 9.5 and 11.9 g Ile kg À1 diet respectively.…”

Dietary phenylalanine-improved intestinal barrier health in young grass carp (Ctenopharyngodon idella) is associated with increased immune status and regulated gene expression of cytokines, tight junction proteins, antioxidant enzymes and related signalling molecules

“…ROS-induced disruption of TJ proteins by reducing the ZO-1 and occludin complex in Caco-2 cell monolayers has been reported [66]. Meanwhile, ROS can induce lipid and protein oxidative damage to destroy the integrity of epithelial cells in the intestine of Jian carp [7]. Thus, we next investigated the effects of Phe on the intestinal TJ proteins and the intestinal integrity for young grass carp to further study the effects of Phe on intestine health.…”

“…Nutrients can modulate the intestinal mucosal immune system partly by influencing the structural integrity of the intestine [6]. Chen et al [7] noted that the normal structure and function of intestine were associated with antioxidant capacity in Jian carp (Cyprinus carpio var. Jian).…”

Changes in barrier health status of the gill for grass carp (Ctenopharyngodon idella) during valine deficiency: Regulation of tight junction protein transcript, antioxidant status and apoptosis-related gene expression

“…Fish gills are a rich source of n-3 polyunsaturated fatty acids (PUFAs) [69,70] and are highly susceptible to oxidative attack by ROS [71,72], which damages the integrity of gill epithelia. MDA and PC content in fish are widely used as convenient indexes of oxidative damage to lipids and proteins, respectively [73].…”