Effects of GSM-Modulated Radiofrequency Electromagnetic Fields on Mouse Bone Marrow Cells

Abstract

We examined the effects of in vivo exposure to a GSM-modulated 900 MHz RF field on the ability of bone marrow cells to differentiate, colonize lymphatic organs, and rescue lethally X-irradiated mice from death. X-irradiated mice were injected with medium alone or containing bone marrow cells from either RF-field-exposed (SAR 2 W/kg, 2 h/day, 5 days/ week, 4 weeks) or sham-exposed or cage control donor mice. Whereas all mice injected with medium alone died, mice that received bone marrow cells survived. Three and 6 weeks after bone marrow cell transplantation, no differences in thymus cellularity and in the frequencies of differentiating cell subpopulations (identified by CD4/CD8 expression) were observed among the three transplanted groups. Mitogen-induced thymocyte proliferation yielded comparable levels in all transplanted groups. As to the spleen, no effects of the RF-field exposure on cell number, percentages of B and T (CD4 and CD8) cells, B- and T-cell proliferation, and IFN-gamma production were found in transplanted mice. In conclusion, our results show no effect of in vivo exposure to GSM-modulated RF fields on the ability of bone marrow precursor cells to home and colonize lymphoid organs and differentiate in phenotypically and functionally mature T and B lymphocytes.

MICROWAVE EFFECT OF 0.9 GHz AND 1.8 GHz CW FREQUENCIES EXPOSED TO UNRESTRAINED SWISS ALBINO MICE

“…The finding in [35], corroborated our results where it was reported that increased level of lipid peroxidation and protein oxidative modification as a result of exposure of mice to GSM frequency leads to significant disorders of function and structure of brain and liver cell in mice. The normal tissue observed in bone marrow throughout this study agrees with the findings of [36] where it is shown that there is no effect on exposure to 0.9 GHz GSM modulated RF EMF to mice at SAR of 2 W/kg, 2 h/day, 5 days a week and for 4 weeks. A report in [13] on the effect of electromagnetic radiation from a mobile phone on mice putting into consideration the answering mode and the standby mode is also in good agreement with the findings presented in this work.…”

“…This emerging technology to date has witnessed a lot of research papers with many contradictions. Most significant researches were done using mice exposed to either GSM frequencies or frequencies around that of GSM as in [8][9][10][11][12][13][14][15][16][17]. Research on haematological parameters in [18] reported that thermal effects of RF EMF was capable of increasing neutrophils and decreased the levels of lymphocytes.…”

Power and Current Induction in Arteries and Blood within Due to UHF Exposure

“…The EMF effect on the health and environment has enjoyed a considerable interest of scientific research [1][2][3][4][5][6][7][8]. Despite the extensive work on the health and safety levels of RF and MW, the impact on human and animal health environment of such high frequency electromagnetic spectrum is still not adequately addressed by the scientific world.…”

“…The incident frequency, in the MW and mmWave range 100GHz), is considered. The induced current densities are calculated as a Naggar; PSIJ, 22(1): [1][2][3][4][5][6][7][8]2019; Article no.PSIJ.…”

Effects of GSM‐modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells

“…In a previous study [Prisco et al, ], we assessed the ability of BMC from mice exposed to Global System for Mobile Communication (GSM)‐modulated 900 MHz RF signals to reconstitute the immune system of X‐irradiated animals. We found that BMC isolated from RF‐exposed mice were able to fully replenish central and peripheral hematopoietic compartments at least on a short term (3–6 weeks).…”