Effects of High and Low Dosage of Haloperidol on the Brain in Relation to Schizophrenic Thought Disorder

Abstract

The drug difference between a low and a high dosage of haloperidol was investigated in 40 acutely ill schizophrenic patients. All patients were classified as being thought disordered or non-thought disordered schizophrenic using psychometric methods. From the pool of 40 patients two groups were randomly chosen for the double-blind study, one group receiving 80 mg of liquid haloperidol daily, the other group 16 mg of liquid haloperidol daily. On 5 days during the 21-day treatment the psychopathological state of the patient was evaluated by means of the AMDP system.

Evaluation des AMDP-Systems anhand der neueren Literatur (1983 bis 1987) - Überblicksarbeit

“…Bellaire et al, 1985). In der Li- Nedopil et al (1985 Woggon & Kuny (1983) Tegeler (1985 Arendt et al (1985) Woggon et al (1986a, 1986c) Woggon et al (1984a, b) Woggon (1984 Bellaire et al (1985b) Tegeler (1983) Tegeler (1985 Meya & Renfordt , 1988) Winter et al (1984) Woggon et al (1986a, 1986c Bel/aire et ) Breyer-Pfaff et al (1983 Schied et al 1983Meya & Renfordt (1986,1988) Klieser & Wolfrum 1985Beckmann & Schmauss (1983) thium-Katamnese der Freien Universität Berlin wird der Krankheitsverlauf der dort betreuten Patienten langfristig mit Hilfe des AMDP-Systems dokumentiert (vgl. Volk u. Mü//er-Oer/inghausen, 1986).…”