Effects of high-dose gamma irradiation on tensile properties of human cortical bone: Comparison of different radioprotective treatment methods

Young’s modulus of trabecular bone at the tissue level: A review

“…However, the high energy accompanied by synchrotron X-rays has been shown to affect the protein arrangement in cortical bone, making it more brittle, and consequently its fracture behavior [84]. Some studies have reported effects of the synchrotron radiation on the mechanical properties of trabecular bone [85,86], while other studies have reported no effect, especially on the Young's modulus [87][88][89]; however results from synchrotron experiments and other high-energy CT analyses should be treated with caution.…”

CORR Insights®: The High-cycle Fatigue Life of Cortical Bone Allografts Is Radiation Sterilization Dose-dependent: An In Vitro Study

“…The current study by Ina et al [6] on the fatigue properties of cortical bone and radiation sterilization dose builds on previous work highlighting the importance of improving our understanding of the relationship between radiation sterilization and mechanical properties [1, 2, 5, 7, 9-12], as well as the chemical composition of cortical bone [4]. Ina et al [6] reported a dose-dependent decrease in fatigue life and a sixfold decrease in the mean cycles to failure of cortical bone between 17.5 kGy and 25 kGy.…”

A Comprehensive Microstructural and Compositional Characterization of Allogenic and Xenogenic Bone: Application to Bone Grafts and Nanostructured Biomimetic Coatings

“…Two femurs were found positive to microbiological controls and irradiated with gamma rays following the Tissue Bank guidelines. Literature studies indicate that significant differences arise in biological and mechanical properties of bones, following gamma irradiation [34][35][36][37]. For this reason, samples from these femurs were included in the experimentation, to preliminary assess if and how the irradiation can also cause alterations in bone composition.…”