“…F I G U R E 1 TRM among young and elderly patients undergoing hematopoietic stem cell transplantation (allo-HSCT) F I G U R E 2 Overall survival of the elderly group undergoing allo-HSCT according to donor type: matched related donor (MRD); matched unrelated donor (MUD) or haploidentical The functional assessment of hospitalised elderly patients may provide a complementary tool to predict survival and life quality in this critical period. (DeFor, Burns, Gold,& Weisdorf, 2007;Hoogerduijn, Schuurmans, Duijnstee, Rooij, & Grypdonck, 2007;Kim et al, 2015;Muffly et al, 2014) Altogether, these features support the possibility that this mortality phenomenon occurs in a multifactorial complex context caused by age-related poor immune reconstitution, host immune dysfunction, chronic GVHD, longer exposure to immunosuppressive drugs and unrecovered loss of functions. As a limiting…”