Effects of Ibuprofen Supplement on Maximal Muscular Strength and Indicators of Muscle Damage Following Exercise-induced Delayed Onset Muscle Soreness

Abstract

This study aimed to investigate the effects of Ibuprofen supplement on delayed onset muscle soreness(DOMS) by analyzing the maximum muscle strength and indicators of muscle damꠓ age. Eighteen men with majors in physical education were assigned to the Ibuprofen group and placebo group in a double-blinded design, and repeated measurements were conducted. DOMS was induced with an isokinetic exercise. Following Ibuprofen administration, the changes in the knee extension peak torque, flexion peak torque, creatine kinase (CK), and lactate dehydrogenase (LDH) concentrations were analyzed. The administration of Ibuprofen inhibits the reduction of the extension peak torque and elevation of CK concentrations. Therefore, Ibuprofen might be administered as a supplement to maintain the muscle strength and prevent muscle damage.