Effects of immobilization upon various metabolic and physiologic functions of normal men

Deitrick, John E.; Whedon, G. Donald; Shorr, Ephraim

doi:10.1016/0002-9343(48)90370-2

Cited by 586 publications

(200 citation statements)

References 35 publications

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“…The process is progressive, and the rate tends to accelerate (74,77,287). The calcium loss appears to be more severe during weightlessness than during bed rest.…”

Section: R+10+17mentioning

confidence: 99%

Cardiovascular Adjustments to Gravitational Stress

Blomqvist

Stone

1983

Comprehensive Physiology

198

163

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“…The process is progressive, and the rate tends to accelerate (74,77,287). The calcium loss appears to be more severe during weightlessness than during bed rest.…”

Section: R+10+17mentioning

confidence: 99%

Cardiovascular Adjustments to Gravitational Stress

Blomqvist

Stone

1983

Comprehensive Physiology

198

163

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“…The inactive life of the lower activity group led to a decrease in circulatory function, which in turn resulted in a higher heart rate than those observed for the other groups, both at rest and during similar activities. This speculation is supported by several early bed rest studies (19)(20)(21), in which it was reported that heart rate at rest and during submaximal exercise increases significantly after a prolonged period in a nonactive state, as represented by the bedridden state. For example, in 1948 Deitrick et al (19) reported that the resting pulse rate while lying in bed increases by 3.8 beats/minute after 6-7 weeks of bed rest, and in 1949 Tailor et al (20) reported that the pulse in a vertically tilted position (65 degrees) increases by 38 beats/ minute after 3 weeks of bed rest.…”

Section: Discussionmentioning

confidence: 73%

“…This speculation is supported by several early bed rest studies (19)(20)(21), in which it was reported that heart rate at rest and during submaximal exercise increases significantly after a prolonged period in a nonactive state, as represented by the bedridden state. For example, in 1948 Deitrick et al (19) reported that the resting pulse rate while lying in bed increases by 3.8 beats/minute after 6-7 weeks of bed rest, and in 1949 Tailor et al (20) reported that the pulse in a vertically tilted position (65 degrees) increases by 38 beats/ minute after 3 weeks of bed rest. In 1968, Saltin et al (21) demonstrated that the increase in heart rate at rest and during submaximal exercise after a prolonged bed rest compensates for a decrease in stroke volume, and that the oxygentransporting ability at rest and during submaximal exercise is maintained by this system.…”

Section: Discussionmentioning

confidence: 73%

Comparison of activity level in daily life with heart rate: Application to elderly persons of different ambulatory abilities

Noda

Saito

Nishizawa

et al. 2006

Environ Health Prev Med

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Objectives: Normal activity monitoring methods are mainly useful for relatively healthy and ablebodied people, but are not necessarily appropriate for elderly persons who may have difficulty in walking, or for the frail who may be bedridden. The purpose of this study was to examine 24-hour heart rate recording for the comparison of activity levels in daily life of elderly persons of different ambulatory abilities.Methods: Forty-two elderly females (mean, 82.1 years old) volunteered to participate in this study. The subjects were divided into four groups on the basis of their ambulatory status, and their 24-hour heart rate recordings were compared with their results of activity assessments.Results: The results of activity assessments showed a tendency to decrease as the ambulatory ability of the group decreased. The "total heart beats", calculated as the sum of all heart rates over 24 hours, were almost the same among the four groups, and therefore did not show a similar tendency. However, the "total excess-beats product (TEBP)" correlated with the results of activity assessments. TEBP was calculated as the sum of all differences in beats between each heart rate in 24 hours and the mean heart rate during sleeping at night. Therefore, TEBP may reflect a more active state than the bedridden state.Conclusions: These results suggest that comparison of activity levels in daily life using 24-hour heart rate recording might be possible by the calculation of TEBP, and that this method might be useful for the comparison of the activity levels of elderly persons of diffent ambulatory abilities.

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“…Deitrick, Whedon and Shorr (1948) found elevated serum calcium levels in their healthy volunteers after they had been immobilised for 5 weeks or longer. Heath et al (1972) found abnormal elevations of serum ionised calcium in nine out of ten patients who were immobilised for the treatment of fractures.…”

Section: Discussionmentioning

confidence: 94%

Hypercalcaemia in adolescent tetraplegic patients: case report and review

1978

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Abstract. The paper presents the case history of a Is-year-old boy with traumatic tetraplegia who developed hypercalcaemia within 6 weeks of injury. The condition was initially controlled by the infusion of intravenous fluids in large amounts and by the administration of calcitonin. Mter 3 weeks, calcitonin became ineffective. Eventually the hypercalcaemia responded to cortisone administered in low dosage. The endo crinologic implications of this observation are discussed.

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Effects of immobilization upon various metabolic and physiologic functions of normal men

Cited by 586 publications

References 35 publications

Cardiovascular Adjustments to Gravitational Stress

Cardiovascular Adjustments to Gravitational Stress

Comparison of activity level in daily life with heart rate: Application to elderly persons of different ambulatory abilities

Hypercalcaemia in adolescent tetraplegic patients: case report and review

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