Effects of intravenous sodium bicarbonate and sodium acetate on equine acid-base status

Kline, Kevin; Frey, L. P.; Foreman, Jonathan H.; Lyman, Joseph T.

doi:10.1016/j.jevs.2005.07.003

Cited by 6 publications

(7 citation statements)

References 11 publications

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“…In dairy cattle, metabolic alkalosis can cause many undesirable effects, like puerperal hypocalcaemia, which happens often in the transition period (MARTÍN-TERESO & MARTENS, 2014). Metabolic alkalosis causes a reduction of the osteoclast activity, leading to a low ionic calcium output in the bloodstream (BUSHINSKY, 1996), it also increases the calcium affinity to its binding proteins, reducing ionic calcium bioavailability and thus aggravating hypocalcaemia (KLINE et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Two enteral solutions with different chloride concentrations administered by naso-ruminal route for fluid therapy in adult cattle

et al. 2019

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Six adult Holstein cows were used in this fluid therapy study. All animals were previously submitted to 24 hours of water and food abstaining period and submitted to both hydration treatments for eight hours in a crossover design 6x2. Two treatments with hypotonic solutions (190 mOsm/L) with low strong ion difference and different chloride concentrations solutions were executed. Physical, biochemical, blood gas analysis and urinary evaluation were executed in five different experimental times (T-24h, T0h, T4h, T8h e T24h). The hydration period caused plasmatic volume expansion. An increase in faeces humidity, excretion of Na+ and Cl- in urine, reduction of PCV, osmolarity, blood and urinary pH was observed. Both solutions can be used for fluid therapy for adult cattle and solution containing calcium chloride (SECaCl) was the most suitable for use in animals with hypochloraemia.

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Section: Introductionmentioning

confidence: 99%

Two enteral solutions with different chloride concentrations administered by naso-ruminal route for fluid therapy in adult cattle

et al. 2019

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“…In contrast, when a smaller amount of NaAcetate (110 g) was given intravenously (i.v.) the increase in plasma [Na + ] was more rapid and less prolonged, occurring from 20–60 min post infusion [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Sodium acetate (NaAcetate) has received some attention as an alkalinizing agent and possible alternative to sodium bicarbonate (NaHCO 3 ) [ 3 ]. In contrast to NaHCO 3 , the ergogenic effects of NaAcetate do not appear to have been studied in horses, however a few studies have demonstrated its alkalinizing effect orally [ 3 ] and intravenously [ 4 ]. Of the limited studies of NaAcetate administration in horses, none have measured and reported the major plasma constituents describing acid-base status, therefore the magnitude and time course of variables that contribute to the origins of the metabolic alkalosis have been incompletely characterized; indeed the picture may be different from that obtained with NaHCO 3 and other alkalinizing compounds.…”

Section: Introductionmentioning

confidence: 99%

The effect of oral sodium acetate administration on plasma acetate concentration and acid-base state in horses

Waller

Lindinger

2007

Acta Vet Scand

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Aim: Sodium acetate (NaAcetate) has received some attention as an alkalinizing agent and possible alternative energy source for the horse, however the effects of oral administration remain largely unknown. The present study used the physicochemical approach to characterize the changes in acid-base status occurring after oral NaAcetate/acetic acid (NAA) administration in horses.Methods: Jugular venous blood was sampled from 9 exercise-conditioned horses on 2 separate occasions, at rest and for 24 h following a competition exercise test (CET) designed to simulate the speed and endurance test of 3-day event. Immediately after the CETs horses were allowed water ad libitum and either: 1) 8 L of a hypertonic NaAcetate/acetic acid solution via nasogastric tube followed by a typical hay/grain meal (NAA trial); or 2) a hay/grain meal alone (Control trial). Results Conclusion:It is concluded that oral NaAcetate could be used as both an alkalinizing agent and an alternative energy source in the horse.

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“…Na prática da clínica de equinos, a administração de bicarbonato de sódio é usual em casos de acidose metabólica, em razão de sua ação alcalinizante (KLINE et al, 2005). Entretanto, o uso desse tampão em animais deve ser feito com cautela, porque o excesso pode trazer danos como alcalose sistêmica iatrogênica, edema cerebral e acidose paradoxal do fluido cérebro-espinhal (LEAL et al, 2007).…”

Section: N Introduçãounclassified

Efeito De Soluções Isotônicas No Equilíbrio Acidobásico Em Potros Sadios

Santos

Curcio

et al. 2017

SCI. ANIM. HEALTH

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Na rotina da clínica médica de equinos, as soluções isotônicas são bastante utilizadas. Entretanto, pouco se sabe sobre seu real efeito no equilíbrio acidobásico em equinos jovens. O objetivo deste estudo foi avaliar o efeito das soluções poliônicas: cloreto de sódio 0,9%, solução de Ringer com lactato e Ringer com lactato acrescido de bicarbonato de sódio sobre o equilíbrio acidobásico em potros. O experimento foi realizado com quatro potros de 18-24 meses, que receberam as três soluções intravenosas em diferentes momentos. Foram realizadas cinco coletas para hemogasometria (T0, T20, T60, T100 e T140), sendo avaliado o pH, pressão parcial de dióxido de carbono (pCO2), pressão parcial de oxigênio (pO2), saturação de hemoglobina por oxigênio (sO2), bicarbonato de sódio (HCO3-) e excesso ou déficit de bases no sangue (BE). A administração de Ringer com lactato acrescido com bicarbonato de sódio promoveu o incremento nas concentrações das variáveis pH, HCO3- e BE, enquanto as demais soluções avaliadas não apresentaram diferença. Embora tenha potencial alcalinizante, a solução de Ringer com lactato acrescida de bicarbonato de sódio demonstrou efeito transitório.

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Effects of intravenous sodium bicarbonate and sodium acetate on equine acid-base status

Cited by 6 publications

References 11 publications

Two enteral solutions with different chloride concentrations administered by naso-ruminal route for fluid therapy in adult cattle

Two enteral solutions with different chloride concentrations administered by naso-ruminal route for fluid therapy in adult cattle

The effect of oral sodium acetate administration on plasma acetate concentration and acid-base state in horses

Efeito De Soluções Isotônicas No Equilíbrio Acidobásico Em Potros Sadios

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