Effects of intraventricular injections of imipramine and 5-hydroxytryptamine on tonic immobility in chickens

Harston, Craig T.; Sibley, David H.; Gallup, Gordon G.; Wallnau, Larry B.

doi:10.3758/bf03335181

Cited by 22 publications

(5 citation statements)

References 11 publications

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“…The possible peripheral effect of tryptophan on body temperature fosters speculation as to whether the effect of tryptophan on food intake may also be peripherally based. In an earlier study, Lacy et al (1984) found that orally administered tryptophan had no effect on tonic immobility, a behavior known to be very sensitive to brain 5-HT manipulation (Maser et al, 1975;Harston et al, 1976;Wallnau and Gallup, 1977;Hennig, 1980). It was postulated at that time that tryptophan might not be influencing food intake by increasing brain 5-HT concentrations.…”

Section: Resultsmentioning

confidence: 95%

Tryptophan’s Influence on Feeding and Body Temperature in the Fowl

et al. 1986

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The neurotransmitter, serotonin, has been implicated in both food intake and body temperature regulation. In this experiment, the effect of tryptophan, the amino acid precursor of serotonin, on food consumption and rectal temperature in the fowl was determined. Single Comb White Leghorn cockerels were intubated with a tryptophan solution or distilled water. Tryptophan significantly (P less than or equal to .05) decreased both food intake and body temperature of the birds. These results suggest that tryptophan may inhibit food intake via peripheral rather than central mechanisms.

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Section: Resultsmentioning

confidence: 95%

Tryptophan’s Influence on Feeding and Body Temperature in the Fowl

et al. 1986

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“…As an example of this phenomenon, centrally administered 5-HT prolongs TI duration in chickens (Harston et al, 1976) but attenuates the reaction in rabbits (Hatton, Tankle, Lanthorn, & Meyer, 1978). Although this reversal is interesting, its mechanisms and significance remain obscure.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, the duration of TI is enhanced by systemic administration of the serotonin precursor L-tryptophan (Boren, Gallup, Suarez, Wallnau, & Gagliardi, 1979;Gallup, Wallnau, Boren, Gagliardi, Maser, & Edson, 1977), the catabolism inhibitors pargyline (Boren et al, 1979;, iproniazid (Maser et al, 1975), and tranylcypromine (Boren, Suarez, & Gallup, Note 1), and the 5-hydroxytryptamine (5-HT) receptor agonists LSD and BOL-148 (Maser et al, 1975). In a similar fashion, intraventricular administration of either 5-HT itself or imipramine, which blocks serotonin reuptake (Harston, Sibley, Gallup, & Wallnau, 1976), prolongs response duration. In contrast, attenuated immobility duration occurs after dietary deprivation of tryptophan (Gallup et al, 1977).…”

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confidence: 99%

p-Chloroamphetamine: Effects on tonic immobility, activity, and temperature in chickens.

Boren¹,

Suarez²,

Gallup³

1981

Journal of Comparative and Physiological Psychology

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“…Epinephrine (Braud and Ginsberg, 1973;Thompson et al, 1977;Hennig et al, 1980), NE, and L-DOPA (Thompson and Joseph, 1978;Ettinger and Thompson, 1978) increased TI duration in chickens. Similarly, 5 -HT injected intraventricularly increased TI duration in chickens (Harston et al, 1976), as did systemic tryptophan in a dose-dependent fashion (Gallup et al, 1977;Boren et aI., 1979). Thus, the objective of the present study was to measure the effects of intragastric intubations of tryptophan and tyrosine on TI.…”

Section: Introductionmentioning

confidence: 91%

Tyrosine and Tryptophan Influence on Tonic Immobility in the Chicken

1984

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The serotonergic and catecholaminergic systems have been shown to affect both tonic immobility and food intake in the domestic fowl. Tryptophan, the amino acid precursor of serotonin, has been demonstrated to influence tonic immobility and food intake when injected intraperitoneally. Tyrosine, amino acid precursor of the catecholamines, is also known to affect food intake when administered orally. In two experiments, tryptophan and tyrosine were intubated intragastrically into male chickens at levels known to affect food intake, and their effect on tonic immobility was measured. Tryptophan and tyrosine delivered intragastrically had no effect on either duration or susceptibility of tonic immobility. These data suggest that changes in appetite observed as a result of orally administered tyrosine and tryptophan were not due to a general inhibition or stimulation of the central nervous system.

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Effects of intraventricular injections of imipramine and 5-hydroxytryptamine on tonic immobility in chickens

Cited by 22 publications

References 11 publications

Tryptophan’s Influence on Feeding and Body Temperature in the Fowl

Tryptophan’s Influence on Feeding and Body Temperature in the Fowl

p-Chloroamphetamine: Effects on tonic immobility, activity, and temperature in chickens.

Tyrosine and Tryptophan Influence on Tonic Immobility in the Chicken

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