Effects of Isoflurane Anesthesia on the Hematologic Values of Rehabilitated Wild Owls

Berg, Kyra J.; Whittington, Julia K.; Watson, Megan K.; Wiggen, Kelly; Blalock, Amanda; Mitchell, Mark A.

doi:10.1647/2017-333

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…However, since isoflurane-based anesthesia is mild compared to other agents, and even restraining methods can influence the values, this volatile gas was chosen for this study. Isoflurane anesthesia impacts hematology and clinical chemistry values when compared to physical restraint, as demonstrated in other mammals (Welch, 1984;Markovic et al, 1993), birds (Granone et al, 2012;Berg et al, 2019), and even A. jamaicensis and P. hypomelanus bats (Heard and Huft, 1998;Strumpf et al, 2020). However, e.g., ketamine-xylazine-based anesthesia is known to have even higher impacts on the results (Widmaier and Kunz, 1993) and since isoflurane mainly acts on neuronal function, the restraining effects on leukocytes are assumed to be diminished quickly.…”

Section: Discussionmentioning

confidence: 99%

Baseline of Physiological Body Temperature and Hematological Parameters in Captive Rousettus aegyptiacus and Eidolon helvum Fruit Bats

et al. 2022

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The discovery of bats as reservoir hosts for a number of highly pathogenic zoonotic agents has led to an increasing interest of infectious disease research in experimental studies with bats. Therefore, we established breeding colonies of Rousettus aegyptiacus and Eidolon helvum fruit bats, which both have been identified as reservoir hosts for relevant zoonotic disease agents, such as Marburg virus and Lagos bat virus. Since 2013, individuals of both species have been recruited to the Friedrich-Loeffler-Institut (FLI) from zoological gardens in Europe, to where these species had been introduced from the wild several decades ago. The aviaries have been designed according to national recommendations published by the Federal Ministry of Agriculture. Under these conditions, both species have been reproducing for years. To better understand the physiology of these animals, and to generate baseline knowledge for infection experiments, we monitored the body core temperatures of R. aegyptiacus bats in the aviaries, and found a circadian variation between 34°C and 41.5°C. We also determined the hematological parameters of both species, and detected specific differences between both bat species. For values of clinical chemistry, no correlation to age or sex was observed. However, species-specific differences were detected since ALT, BUN and CREA were found to be significantly higher in R. aegyptiacus and GLU and TP were significantly higher in E. helvum bats. A higher hematocrit, hemoglobin and red blood cell level was observed in subadult R. aegyptiacus, with hemoglobin and red blood cells also being significantly increased compared to E. helvum. Lymphocytes were found to be the dominant white blood cells in both species and are higher in female E. helvum. Neutrophil granulocytes were significantly higher in E. helvum bats. This underlines the necessity to define baseline profiles for each bat species prior to their use in experimental challenge.

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Section: Discussionmentioning

confidence: 99%

Baseline of Physiological Body Temperature and Hematological Parameters in Captive Rousettus aegyptiacus and Eidolon helvum Fruit Bats

et al. 2022

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“…In addition, our study did not take into account the possible pregnancy in cows, which could have caused a change in some blood parameters. Another limitation can be the effect of anesthesia on blood cell counts and plasma biochemical values which has been described in other species [66][67][68]. Despite the above limitation, our study presents blood parameters carried out for the first time on a group of healthy animals, using robust analytical methods, which provides a basis for their use.…”

Section: Plos Onementioning

confidence: 99%

Determination of hematological and biochemical values blood parameters for European bison (Bison bonasus)

Didkowska,

Klich,

Anusz

et al. 2024

PLoS ONE

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Hematological and biochemical blood parameters are important tools for evaluating animals’ health. They might be crucial in assessing the health of entire populations of wild animals, such as European bison (Bison bonasus). The aim of this study was to establish hematological and biochemical values for healthy European bison and to determine whether there were significant relations with age and sex. Blood samples were collected from 79 animals and tested according to generally accepted standards and the results were subjected to statistical analysis. Most of the age and gender-related correlations found in our study were predictable based on previous reports. Due to bone growth, juvenile animals have typically higher ALP and P concentrations relative to adults. Several age-related dependencies were surprising, like higher Na concentration in younger European bison. Determination of hematological and biochemical blood parameters of healthy European bison may significantly contribute to the further restitution of this endangered species.

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Effects of Isoflurane Anesthesia on the Hematologic Values of Rehabilitated Wild Owls

Cited by 2 publications

References 28 publications

Baseline of Physiological Body Temperature and Hematological Parameters in Captive Rousettus aegyptiacus and Eidolon helvum Fruit Bats

Baseline of Physiological Body Temperature and Hematological Parameters in Captive Rousettus aegyptiacus and Eidolon helvum Fruit Bats

Determination of hematological and biochemical values blood parameters for European bison (Bison bonasus)

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