Effects of lead exposure on pregnancy outcome and the fetal brain of squirrel monkeys.

Lögdberg, Bengt; Berlin, Maths; Schütz, Andrejs

doi:10.5271/sjweh.2069

Cited by 14 publications

(1 citation statement)

References 26 publications

(32 reference statements)

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“…We are all exposed to many chemicals present in the environment, which enter the body by inhalation, food consumption and/or skin contact. Some studies have found that maternal exposure to heavy metals during pregnancy influences the newborn's height, weight , neurological development , and immune development . Other studies have demonstrated that the fetus is indeed exposed to the environmental and dietary pollutants with which the mother is in contact during pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Prenatal exposure to selenium may protect against wheezing in children by the age of 3

Baïz

Chastang

Ibáñez

et al. 2016

Immunity Inflam & Disease

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IntroductionIt has been suggested that human in utero exposure to heavy metals such as selenium can reduce the prevalence of childhood asthma and allergic diseases. However, data on this topic are scarce. The objective of the present study was to assess the putative associations between maternal selenium level during pregnancy and the risk of asthma, wheezing, allergic rhinitis, and atopic dermatitis in children from the EDEN birth cohort by the age of 1 and 3 years.MethodsPlasma selenium concentrations were measured in maternal blood during mid‐pregnancy (24–28 weeks of gestation) in 861 mothers. Cohort children were followed up from birth to 3 years using health questionnaires filled out by the parents for asthma, wheezing, allergic rhinitis, and atopic dermatitis. Maternal plasma selenium was related to the childhood outcomes by the age of 1 and 3 years.ResultsOur results showed a significant negative association between a high maternal plasma selenium level during pregnancy and the risk of wheezing in the child by the age of 1 and 3 years. However, maternal plasma selenium during pregnancy was not associated with the prevalence of asthma, allergic rhinitis or atopic dermatitis.ConclusionsThe results of this study suggest that the level of fetal exposure to maternal selenium could have an influence on the risk of wheezing in infancy and potentially on the risk of developing asthma later in life.

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Section: Introductionmentioning

confidence: 99%