Effects of Low Atmospheric Pressures on the Activity of the Thyroid, Reproductive System and Anterior Lobe of the Pituitary in the Rat

The Effects of Low Atmospheric Pressure on the Fertility of Male Rabbits

“…Pincus & Hoagland (1943) report an increase in 17-ketosteroids in the urine of animals exposed to low atmospheric pressure. Gordon et al (1943) found that the potency of the gonadotropic hormone of the pituitary glands of rats exposed to low atmospheric pressure is significantly greater than in normal rats. One cannot, therefore, at this stage, exclude the possibility that the effect upon the testis is an indirect one and due to hormonal disturbance.…”

Effect of Acute Hypoxia on Blood TSH Levels

“…The histologieal studies have given controversial results, in some of them hypoplastie or r~sting images of the thyroid were deseribed (Gordon et al 1943;Surks 1966) while hyperplastie ehanges of the glands were shown in others (Johnson and La Roche 1968;Mart;n, Wertenberger and Bullard 1971).…”

“…Some authors have eonsidered they were due to deereased seeretion on thyrotropin (Surks 1969;Galton 1972) while others have thought that the seeretion of this honnone was inereased (Johnson and La Roche 1968;Martin, Wertenberger and Bullard 1971). Using a biologieal method Gordon et al (1943) have shown deereased blood TSH. In the experiments of Nelson and Cons (I975) where newbom rats were bred in ehronie hypoxia eonditions during 40 days no signifieant ehanges were deteeted in blood TSH by radioimmunoassay.…”

Growth of lowland native children of European Ancestry during sojourn at high altitude (3,200 m)

“…It is generally assumed that growth retardation at high altitude is the direct result of hypoxic stress, and experimental evidence on animals tends to support this view (Gordon et al, 1943;Moore and Price, 1948;Timeras, 1962;Cheek et al, 1969). However, children native to high-altitude regions are usually from the poorer socioeconomic strata of their societies, and so face the additional stresses of malnutrition, poor hygiene, inadequate medical care, and overcrowding (Frisancho and Baker, 1970).…”