Effects of low versus physiologic plasma progesterone concentrations on ovarian follicular development and fertility in beef cattle

Pfeifer, Luiz Francisco Machado; Mapletoft, R.J.; Kastelic, John P.; Small, J. A.; Adams, Gregg P.; Dionello, Nelson José Laurino; Singh, Jaswant

doi:10.1016/j.theriogenology.2009.07.019

Cited by 78 publications

(42 citation statements)

References 52 publications

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“…Perry et al [17] also found that a large POF is responsible for a large CL as well as a successful pregnancy. These findings support the theory established by the studies in dairy cattle that a large POF generates a large CL [16,19]. It is likely that fewer cells are present in smaller POFs, which may yield fewer luteal cells subsequent to ovulation compared with larger POFs [20,21].…”

Section: Relationship Between the Pof And The Subsequent CL And Pregnsupporting

confidence: 88%

Preovulatory Follicular and Subsequent Luteal Size Influence Pregnancy Success in Water Buffaloes

Rahman

Shohag

Kamal

et al. 2012

Journal of Reproduction and Development

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Abstract. The diameter of the preovulatory follicle (POF) and its effects on subsequent corpus luteum (CL) size and conception were studied in 38 lactating indigenous cycling buffaloes in the Mymensingh district of Bangladesh. Body condition score (BCS) at estrus was estimated for the buffaloes. The buffaloes were synchronized with two injections of a synthetic analogue of PGF2 α administered 11 days apart. Transrectal ultrasonography was carried out at estrus and on days 5, 9, 12 and 16 post ovulation to determine the POF and successive CL size. Pregnancy was confirmed by ultrasound examination on day 40-45 post ovulation. Twenty one (55.3%) buffaloes were diagnosed as pregnant. The conception rates of thin (BCS ≤2.0), good (BCS 2.5-3.5) and fat (BCS >3.5) buffaloes were 7.7, 88.2 and 62.5% (χ 2 = 19.54; P<0.05), respectively. The mean diameter of the POF at estrus was larger (P<0.01) in buffaloes that ultimately were diagnosed as pregnant compared with their nonpregnant counterparts (13.7 ± 0.3 vs. 11.2 ± 0.5 mm, respectively). The conception rates of buffaloes having small (9 to ≤ 12 mm), medium (>12 to ≤14 mm) and large (>14 to 16 mm) POFs at estrus were 9.1, 70.0 and 85.7% (χ 2 = 13.87, P<0.01), respectively. On day 5 post ovulation, CL size was positively correlated (CL: r=.74, P<0.01) with POF diameter. Retrospective analysis revealed that on day 5 post ovulation, the pregnant buffaloes had higher (P<0.01) post ovulation CL sizes than their nonpregnant counterparts (15.6 vs. 11.8 mm). Similarly, on day 9 post ovulation, the difference in CL size (14.3 vs. 13.6 mm) between pregnant and nonpregnant buffaloes was significant (P<0.05). In conclusion, the diameter of the POF in buffaloes has a positive impact on the size of the post ovulation CL and conception. Key words: Corpus luteum (CL), Preovulatory follicle (POF), Water buffalo (J. Reprod. Dev. 58: [219][220][221][222] 2012) T he preovulatory follicle (POF) is the prime structure behind the endocrinology of estrus in buffaloes that produces substantial amounts of estradiol. A positive correlation exists between the diameter of the POF and plasma estradiol concentration and the subsequent pregnancy rate in cattle [1,2]. It is speculated that the POF diameter is important for the subsequent development of the corpus luteum (CL) and hence conception in buffaloes. A larger POF may generate a larger CL that secretes more progesterone and thereby have a positive effect on pregnancy recognition and pregnancy rates in cattle [3,4]. On the other hand, others have reported absence of correlation [5] or negative correlation [6] between POF diameter and pregnancy outcome. For successful pregnancy, the preovulatory follicle and subsequent luteal size may be important in the indigenous buffaloes. But reports on such work in indigenous buffalo of Bangladesh are not available in the literature. So, it is important to investigate the relationship of POF size and subsequent CL size and pregnancy rate. Use of ultrasonic imaging of ovarian follicular and luteal developme...

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Section: Relationship Between the Pof And The Subsequent CL And Pregnsupporting

confidence: 88%

Preovulatory Follicular and Subsequent Luteal Size Influence Pregnancy Success in Water Buffaloes

Rahman

Shohag

Kamal

et al. 2012

Journal of Reproduction and Development

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“…Serum was harvested and stored at -20°C until Radioimmunoassay (RIA). Serum progesterone was determined using a commercial solid-phase RIA kit containing anti progesterone antibody-coated tubes, and I 125 -labeled progesterone (Immunotech, Beckman Coulter, France) (Pfeifer et al, 2009). The serum progesterone concentration was expressed in nanograms per milliliter (ng/ml).…”

Section: Selection Of Animalsmentioning

confidence: 99%

Effect of preovulatory follicle on fertility in Graded murrah buffaloes (Bubalus bubalis)

Raj

Naidu

Marmamula

et al. 2017

IJAR

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An investigation was taken up to study the relationship of preovulatory follicle size at the time of first postpartum AI and CL biometry with conception using transrectal ultrasonography in 70 parous Graded Murrah buffaloes maintained under rural conditions. POF sizes were measured ultrasonographically and grouped in to small preovulatory follicle (SPF), medium preovulatory follicle (MPF) and large preovulatory follicle (LPF). Serum progesterone concentration at the time of AI and pregnancy status was negatively correlated indicating that when progesterone level declined to < 0.3 ng/ml (basal level) at the time of AI, the chances of the animal becoming pregnant was increased. The size of the POF was positively correlated to the size of the CL on day 10 in pregnant buffaloes. The overall POF diameter at the time of estrum was 12.31 ± 0.29 mm (Range 9 to 16 mm) in Graded Murrah buffaloes and 50 % of the buffaloes had POF size > 12 -14 mm. They conceived only if the POF diameter was more than 9 mm at the time of AI however there was no significant correlation between the POF size at the time of AI and conception. Thus, it was concluded that physiological maturity rather than the diameter of the follicle influenced the fertility in Graded Murrah buffaloes under field conditions.

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“…The optimal size of the ovulatory follicle under hormonal protocols is still a major area of interest, since well-balanced follicular growth is dependent upon multiple hormonal interactions Colazo et al, 2008;Pfeifer et al, 2009;Sá Filho et al, 2010;Dadarwal et al, 2013;, breed characteristics and environmental adaptation (Bó et al, 2003;Baruselli et al, 2004;Sartori and Barros, 2011), and reproductive cyclicity status (Atkins et al, 2010a, b). The ovulatory follicle size in cows and heifers can be assessed from distinct studies; however, no experimental design with animals under the same conditions and without the interference of suckling calves has been conducted in beef cattle.…”

Section: Introductionmentioning

confidence: 99%

Relationships between follicle and corpus luteum diameter, blood flow, and progesterone production in beef cows and heifers: preliminary results

2016

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The aim of the present study in beef cattle was to investigate potential differences in follicle size and follicle wall-blood flow between cows and heifers and to compare follicle wall-blood flow between smaller and larger follicles. Cows and heifers were treated with a synchronization protocol and follicles and CLs were measured and evaluated for blood flow. Pregnancy diagnosis was performed on day 50 of the protocol. Cows had larger (P < 0.008) follicles than heifers. Cows, heifers, and pregnant and non-pregnant cows did not differ (P > 0.05) in CL diameter, CL blood flow, and plasma progesterone concentrations. Moderate correlations between follicle diameter and follicle blood flow were observed for cows (r = 0.51; P < 0.002) and heifers (r = 0.61; P < 0.0001). Pregnant cows tended (P < 0.1) to have larger follicles between 12 to 60 h before ovulation, and had larger (P < 0.05) follicles than non-pregnant cows at hour 24 before ovulation and at hour 12 before maximum values. Pregnant cows had greater (P < 0.05) follicle blood flow than non-pregnant cows at hours −36 and −24 before maximum values. Follicle blood flow was greater (P < 0.002) in the large follicles compared with the small follicles, and tended (P < 0.06) to be greater than in medium follicles. Moderate to strong correlations were found between follicle blood flow and diameter of small (r = 0.59; P < 0.002), medium (r = 0.50; P < 0.02), and large (r = 0.71; P < 0.0001) follicles. Pregnancy rates were similar (P > 0.05) among all follicle diameter categories. In conclusion, synchronized beef cows and pregnant cows had larger follicles and greater blood flow than heifers and non-pregnant cows, and follicle wall blood flow was closely associated with increasing follicle diameter.

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Effects of low versus physiologic plasma progesterone concentrations on ovarian follicular development and fertility in beef cattle

Cited by 78 publications

References 52 publications

Preovulatory Follicular and Subsequent Luteal Size Influence Pregnancy Success in Water Buffaloes

Preovulatory Follicular and Subsequent Luteal Size Influence Pregnancy Success in Water Buffaloes

Effect of preovulatory follicle on fertility in Graded murrah buffaloes (Bubalus bubalis)

Relationships between follicle and corpus luteum diameter, blood flow, and progesterone production in beef cows and heifers: preliminary results

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