2009
DOI: 10.4102/jsava.v80i2.175
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Effects of lumbosacral epidural ketamine and lidocaine inxylazine-sedated cats : article

Abstract: In order to determine the analgesic and cardiovascular effects of the combination of epidural ketamine and lidocaine, 6 sedated cats were studied. Six healthy, young cats were used in a prospective randomised study. Each cat underwent 3 treatments, at least 1 week apart, via epidural injection: (1) ketamine (2.5 mg/kg), (2) lidocaine (4.0 mg/kg), and (3) ketamine (2.5 mg/kg) plus lidocaine (4.0 mg/kg). Epidural injections were administered through the lumbosacral space. Analgesia, motor block, sedation, heart … Show more

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Cited by 16 publications
(4 citation statements)
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“…Co-administration of ketamine and lidocaine epidurally increased duration of caudal analgesia in cats and dogs compared with administration of lidocaine or ketamine alone (DeRossi et al 2009;DeRossi et al 2011). Moulvi et al (2011) evaluated caudal analgesic effects following epidural injection of lidocaine and a combination of lidocaine and ketamine in cow calves.…”
Section: Discussionmentioning
confidence: 99%
“…Co-administration of ketamine and lidocaine epidurally increased duration of caudal analgesia in cats and dogs compared with administration of lidocaine or ketamine alone (DeRossi et al 2009;DeRossi et al 2011). Moulvi et al (2011) evaluated caudal analgesic effects following epidural injection of lidocaine and a combination of lidocaine and ketamine in cow calves.…”
Section: Discussionmentioning
confidence: 99%
“…The combination of ketamine with lidocaine has shown prolonged analgesic effects in cats, though severe ataxia was observed. Despite some studies highlighting ketamine's analgesic potential, its use is cautioned against until more information on its neurotoxic effects is available [20][21][22][23][24] emphasize that ketamine should not be administered epidurally or intrathecally until further studies report its neurotoxic effects.…”
Section: Ketaminementioning
confidence: 99%
“…The combination of ketamine with lidocaine has shown prolonged analgesic effects in cats, though severe ataxia was observed. Despite some studies highlighting ketamine's analgesic potential, its use is cautioned against until more information on its neurotoxic effects is available [20][21][22][23][24] emphasize that ketamine should not be administered epidurally or intrathecally until further studies report its neurotoxic effects.…”
Section: Ketaminementioning
confidence: 99%