Effects of meteorological factors on the onset of Bell's palsy

Jeon, Eun-Ju; Park, Yong Soo; Kim, Dong-Hyun; Nam, In Chul; Park, Soyoung; Noh, Heil; Yeo, Sang Won

doi:10.1016/j.anl.2012.10.008

Cited by 18 publications

(14 citation statements)

References 19 publications

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“…They found both season and climate (adjusted ratio of cold to warm months = 1.31) were independent predictors of risk of Bell's palsy [78][79][80] There is a clear relationship between the cold season and the number of cases observed. However, some researchers have found that BP is more frequent in warm seasons (spring and summer), with its incidence peaking in September [81] More deeply, one study evaluated the influences of meteorological factors on the incidence and onset of BP. Evidence suggests that stronger wind speed of preceding day may be related to the occurrence of Bell's palsy [82] One study retrospectively reviewed 568 files of Bell's palsy patients and concomitant data of meteorological factors.…”

Section: Anatomical Structurementioning

confidence: 99%

The etiology of Bell’s palsy: a review

et al. 2019

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Bell's palsy is the most common condition involving a rapid and unilateral onset of peripheral paresis/paralysis of the seventh cranial nerve. It affects 11.5-53.3 per 100,000 individuals a year across different populations. Bell's palsy is a health issue causing concern and has an extremely negative effect on both patients and their families. Therefore, diagnosis and prompt cause determination are key for early treatment. However, the etiology of Bell's palsy is unclear, and this affects its treatment. Thus, it is critical to determine the causes of Bell's palsy so that targeted treatment approaches can be developed and employed. This article reviews the literature on the diagnosis of Bell's palsy and examines possible etiologies of the disorder. It also suggests that the diagnosis of idiopathic facial palsy is based on exclusion and is most often made based on five factors including anatomical structure, viral infection, ischemia, inflammation, and cold stimulation responsivity.

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Section: Anatomical Structurementioning

confidence: 99%

The etiology of Bell’s palsy: a review

et al. 2019

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“…Bell's palsy is most likely to represent an autoimmune reaction in response to a component of the peripheral nerve myelin, leading to demyelination of the facial nerve (Greco et al, ). This autoimmune disease can be triggered by a viral infection as well as acute cold (Jeon et al, ; Khedr et al, ; Kokotis & Katsavos, ; Wakisaka et al, ) and accounts for 60%–75% of all cases of unilateral facial paralysis (Adel, Kawthar, Amine, Youssef Souha, & Abdellatif, ). Subcutaneous fat is the primary line of defense against cold stimuli, which can release various secretory factors or adipokines that signal the immune system (Huh, Park, Ham, & Kim, ; Vielma, Klein, Levingston, & Young, ).…”

Section: Discussionmentioning

confidence: 99%

Immune‐related gene expression profiles of hypothermia adipocytes: Implications for Bell's palsy

Zhang

Luo

et al. 2019

Oral Diseases

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Objective To identify immune‐related gene expression profiles of adipocytes under low temperatures with RNA sequencing as a model for Bell's palsy implications. Methods Adipocytes were harvested from the white adipose tissue of male Sprague‐Dawley rats and cultured under different acute‐grade cold exposure conditions of 30, 20, and 10°C, and their genomes were sequenced for RNA sequencing analysis. The differentially expressed genes (DEGs) were validated with reverse transcription polymerase chain reaction. Results In total, 55 (35 upregulated and 20 downregulated), 121 (76 upregulated and 45 downregulated), and 92 (64 upregulated and 28 downregulated) DEGs were identified under 30, 20, and 10°C compared with the control, respectively. KEGG and GO analysis revealed that the DEGs were considerably enriched in immune‐related pathways (leukocyte transendothelial migration and platelet activation) and infection (bacterial invasion of epithelial cells and Salmonella infection). The levels of key inflammatory chemokines (CSF1, CXCL1, CCL2, and CCL7) were enhanced after cold exposure. Conclusion These findings broaden our understanding of the immune responses to cold exposure in adipocytes. The molecular profiles of adipocyte immune function will help clarify the potential mechanism impacting myelin, which might contribute to the development of strategies to control Bell's palsy.

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“…In addition, there are definitive diagnoses between Bell's palsy and post-traumatic facial paralysis, Lyme disease, Melkersson-Rosenthal syndrome, Sjögren syndrome, cholesteatoma. Of these, although Melkerson-Rosenthall syndrome, which is also known as recurrent paralysis, has symptoms such as blanking of sulcus nasolabialis, not being able to close the eyleids and fissure on tongue which are similar to Bell's palsy, its pathophysiology is different (7,16,17).…”

Section: Bell's Palsy Diagnosis and Assessment Methodsmentioning

confidence: 99%

“…In addition, electrogustometry is preferred in this test since it is fast and easy. In a study conducted with electrogustometry in the acute phase of Bell's palsy, it was found that the threshold value of taste were different in both sides of the tongue (16,17). The sense of taste has been seen to collapse on the paralyzed side.…”

Section: Definitive Diagnosis In Bell's Palsymentioning

confidence: 99%

Physiotherapy outweighed multiple therapy methods of bell's palsy: a review study

Calisgan¹,

Şenol²,

Çay³

2017

J Turgut Ozal Med Cent

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Although its etiology is not known, Bell's palsy is commonly based on trauma, infection, nervous damage due to surgery, genetic predisposition, autoimmune disease, temporal bone fracture, cerebellar arachnoid cyst and viral infection associated with vascular ischemia and inflammation. Viral infection due to herpes zoster and herpes simplex is the most common known cause of Bell's palsy. It is seen in about 20-35 out of 100.000 people each year. Its incidence is low in children under the age of 14 and it is more frequent within the range of 15-45 years. It is also known to occur equally in men and women. In the third trimester of pregnancy and postpartum in the first week, its frequency increases 3-fold. Unilateral paralysis, lagophthalmos, keratitis, droop of eyelid and edge of mouth, mouth and eye dryness, conjunctivitis and decreasing sensation and 2/3 taste of luxury in front of lingua are its common symptoms. 3 days from the onset of palsy, patients begin to use corticosteroid and antiviral drugs. 71% of patients had improvement after recovery but 29% of patients were shown to have hemifacial weakness and residual sequela throughout life. Synkinesis is the most common sequela of Bell's palsy. The effects of physiotherapy methods and their different combinations with other methods on prognosis were discussed in the treatment of Bell's palsy.

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Effects of meteorological factors on the onset of Bell's palsy

Cited by 18 publications

References 19 publications

The etiology of Bell’s palsy: a review

The etiology of Bell’s palsy: a review

Immune‐related gene expression profiles of hypothermia adipocytes: Implications for Bell's palsy

Physiotherapy outweighed multiple therapy methods of bell's palsy: a review study

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