Effects of Multivitamin/Mineral Supplementation on Trace Element Levels in Serum and Follicular Fluid of Women Undergoing in Vitro Fertilization (IVF)

Özkaya, Mehmet Okan; Nazıroğlu, Mustafa; Barak, Cihan; Berkkanoğlu, Murat

doi:10.1007/s12011-010-8637-x

Cited by 75 publications

(57 citation statements)

References 26 publications

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“…They suggested that these molecules may be effective in quenching excessive generation of free radicals, but they do not seem to play a contributory role in achieving successful pregnancy following IVF. This is an important observation in view of the fact that several groups have the opinion that antioxidants, mineral and vitamin supplementation may considerably improve the IVF success rate [42,43]. However, our study conflicts with the results of some other studies [8,36,44], which observed that lower levels of antioxidants predict decreased fertilization potential.…”

Section: Discussioncontrasting

confidence: 95%

Determination of oxidative stress balance in follicular fluid

Fabjan

Vrtačnik-Bokal

Kumer

et al. 2018

LaboratoriumsMedizin

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Background: The role of oxidative stress in female reproduction is an area that needs more investigation. This study aims to assess the oxidative stress levels in follicular fluid (FF) samples of women undergoing in vitro fertilization (IVF) and to relate them to different diagnoses. Methods: A total of 199 woman were enrolled; 37 of them were diagnosed with polycystic ovary syndrome (PCOS), 71 with endometriosis and 41 with tubal factor infertility (TFI) and 50 of the patients were used as a control group. A sample of FF was collected from each patient at an oocyte retrieval day and analyzed for oxidative stress by measuring a class of reactive oxygen metabolites (ROMs) (dROMs test) and also analyzed for the plasma antioxidant test (PAT). Results: The data analyzed in FF were related to different diagnoses. Groups were not significantly different in age and body mass index (BMI), except for the PCOS group. There was a significant difference between dROMs and PAT levels in FF of patients vs. control group. The same finding was seen when the dROM/PAT ratio was used. Conclusions: We conclude that the evaluation of oxidative stress in FF needs more investigation with regard to markers in the follicular microenvironment.

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Section: Discussioncontrasting

confidence: 95%

Determination of oxidative stress balance in follicular fluid

Fabjan

Vrtačnik-Bokal

Kumer

et al. 2018

LaboratoriumsMedizin

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“…The finding of increased le vels of Cu in OJ rats in our study was supported by the results of Devipriya et al (13). Excess cumulation of Cu in rats triggers oxidative damage of the kidney and liver tissue DNAs and ultimately contributes to many degenerative disorders (19). In this study we observed that OJ group had higher levels of serum and liver Cu, respectively (p<0.001 and p=0.003), than other groups.…”

Section: Discussionsupporting

confidence: 90%

Effects of Erythropoietin on the Serum and Liver Tissue Levels of Copper and Zinc in Rats with Obstructive Jaundice / Efekti Eritropoetina Na Nivoe Bakra I Cinka U Serumu I Tkivima Jetre Kod Pacova Sa Opstruktivnom Žuticom

Aliosmanoglu¹,

Kapan²,

Gül³

et al. 2013

Journal of Medical Biochemistry

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SummaryBackground: Erythropoietin is an anti-apoptotic, anti-inflammatory, angiogenetic cytokine and has protective properties against oxidative stress. In this study we investigated the effects of erythropoietin on the le vels (serum and liver tissue) of copper and zinc in cholestatic rats. Methods: Thirty-two Wistar albino rats used in the study were divided into four groups -Group I: Sham; Group II: Erythropoietin; Group III: Obstruc tive Jaundice; Group IV: Obstructive Jaundice+Erythro poietin. After the first operation, rats were followed up for seven days and then operated for the second time. Rats were sacrificed by intracardiac blood taking, and the liver tissue samples were obtained immediately. Results: Erythropoietin reduces copper, and increases zinc levels in serum and liver tissues after obstructive jaundice (p<0.05). Furthermore, it has been shown that the levels of alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase and total bilirubin/direct bilirubin were significantly lower in Obstructive Jaundice+Erythropoietin group than Obstructive Jaundice group. Conclusions: Erythropoietin affects the changes in copper and zinc levels, thus decrea sing the liver damage biochemically in rats with obstructive jaundice. However, further investigations are needed to discover how erythropoietin therapy might reduce target organ damage in cholestatic liver cases by affecting copper and zinc levels.

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“…Cu is an essential element that plays a role in the production of hemoglobin, myelin, collagen, and melanin [24]. Cu deficiency affects various physiological functions that may be important in immunological defense to pathogenic challenge [25,26]. Cu has also function as cofactor of SOD and CAT in antioxidant redox system [26,27].…”

Section: Discussionmentioning

confidence: 99%

Effects of Shock Waves on Oxidative Stress, Antioxidant Enzyme and Element Levels in Kidney of Rats

Geçit

Kavak

Meral

et al. 2011

Biol Trace Elem Res

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The aim of this study was to investigate the effect of extracorporeal shock wave lithotripsy (ESWL) on kidney oxidative stress and trace element levels of adult rats. Twelve male Wistar albino rats were divided equally into two groups. First group was used as control. The right-side kidneys of animals in second group were treated with 2,000 18-kV shock waves under anesthesia. Localization of the right kidney was achieved following contrast medium injection through a tail vein under flouroscopy control. The animals were sacrificed 72 h after the ESWL treatment, and the kidneys were taken. Malondialdehyde level was higher in the ESWL group than in the control. Reduced glutathione levels, superoxide dismutase, and glutathione peroxidase activities were lower in the ESWL group than those of the control. Fe, Cu, Pb, Mn, Cd, and Ni levels were lower in the ESWL group than in the control, although Mg level was higher in the ESWL group than in the control. In conclusion, the result of the present study indicated that ESWL treatment produced oxidative stress in the kidney and caused impairments on the antioxidant and trace element levels in the kidneys of rats.

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Effects of Multivitamin/Mineral Supplementation on Trace Element Levels in Serum and Follicular Fluid of Women Undergoing in Vitro Fertilization (IVF)

Cited by 75 publications

References 26 publications

Determination of oxidative stress balance in follicular fluid

Determination of oxidative stress balance in follicular fluid

Effects of Erythropoietin on the Serum and Liver Tissue Levels of Copper and Zinc in Rats with Obstructive Jaundice / Efekti Eritropoetina Na Nivoe Bakra I Cinka U Serumu I Tkivima Jetre Kod Pacova Sa Opstruktivnom Žuticom

Effects of Shock Waves on Oxidative Stress, Antioxidant Enzyme and Element Levels in Kidney of Rats

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