2023
DOI: 10.1017/s0967199422000557
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Effects of myo-inositol plus folic acid on ovarian morphology and oocyte quality in PCOS mouse model

Abstract: Summary Although the role of myo-inositol (MYO) in promoting the oocyte quality of PCOS patients has been documented in human studies; the cellular effects of this supplement on oocytes have not been directly examined due to ethical limitations. In the first phase of this study, MYO dosimetry was carried out simultaneously with the PCOS model development. An effective dose was obtained following the assessment of fasting insulin and testosterone levels using ELISA and ovarian morphology appraisal by histopa… Show more

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Cited by 4 publications
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“…The clinical symptoms are hyperandrogenism, polycystic ovaries, and chronic oligo (50). The reported animal models of PCOS include mice (51), pigs (52), rats (53), sheep (54), and cattle (55). Many studies have analyzed the enzymes involved in steroid hormone transformation.…”
Section: Androgen Transformation and Transportation In Vivomentioning
confidence: 99%
“…The clinical symptoms are hyperandrogenism, polycystic ovaries, and chronic oligo (50). The reported animal models of PCOS include mice (51), pigs (52), rats (53), sheep (54), and cattle (55). Many studies have analyzed the enzymes involved in steroid hormone transformation.…”
Section: Androgen Transformation and Transportation In Vivomentioning
confidence: 99%