2014
DOI: 10.1590/1809-2950/278210114
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Effects of nandrolone decanoate on the viability of muscle satellite cells during the differentiation process

Abstract: | Studies indicate that the anabolic nandrolone decanoate (Deca-Durabolin®) can modulate cell cycle regulation, but little is known about its effects on muscle cells. Anabolic steroids are used, especially by athletes, to improve muscle mass and performance in the practice of exercises. The aim of this study was to evaluate the effect of the anabolic Deca-Durabolin® on the proliferation of skeletal muscle precursor cells C2C12. Cells were grown in Dulbecco's Modified Eagle Medium (DMEM), being supplemented wit… Show more

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“…During the process of fusion, some myonuclei may remain in the central area of the out coming new and larger fiber. This central myonuclei is needed for the growth of the new fiber when new myotubes unite with the already existing muscle fiber [30,34,37].…”
Section: Discussionmentioning
confidence: 99%
“…During the process of fusion, some myonuclei may remain in the central area of the out coming new and larger fiber. This central myonuclei is needed for the growth of the new fiber when new myotubes unite with the already existing muscle fiber [30,34,37].…”
Section: Discussionmentioning
confidence: 99%