Effects of Nasal Application of an Epinephrine and Lidocaine Mixture on the Hemodynamics and Nasal Mucosa in Oral and Maxillofacial Surgery

Kameyama, Kimiko; Watanabe, Seiji; Kano, Tatsuhiko; Kusukawa, Jingo

doi:10.1016/j.joms.2008.01.013

Cited by 24 publications

(19 citation statements)

References 21 publications

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“…Many hemodynamic studies were carried out on patients subjected to local anesthesia with vasoconstrictor. [13,14,15,16] No significant changes were recorded in either blood pressure (systolic and diastolic) or heart rate. However, some authors suggested that such changes were dependent upon the injected vasoconstrictor dose.…”

Section: Discussionmentioning

confidence: 96%

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Al-Saffar¹,

Al–Sandook²,

Taha³

2014

AJPS

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Aim: To study the effects of local anesthesia on blood pressure in patients undergo extraction of maxillary teeth under infiltration local anesthesia and to compare the level of salivary chromogranin A before and after administration of local anesthesia and its possible correlation with hemodynamic effects of local anesthesia. Materials and Methods: A total of 26 patients (18 female, 8 male) who need tooth extraction under infiltration local anesthesia were examined in two situations (pre and post local anesthetic administration). For each patient salivary sample was collected by salivette to estimate the level of chromogranin A using ELISA Kits. For all patients, the blood pressure and pulse rate were measured before and after administration of local anesthesia using automatic blood pressure recorder. Results: the results showed significant differences between salivary chromogranin A for patients before the administration of local anesthesia (580.33 ± 130.42) ng/ml and after the administration of local anesthesia (674.51+ 130.93) ng/ml with p < 0.05. The results also showed that the mean value of blood pressure (systolic and diastolic blood pressure) lowered after administration of local anesthesia but with no significant differences (p > 0.05) with pre -local anesthetic value. The pulse rate was increase in it is value after local anesthetic administration with a significant differences (p < 0.05) than pre -anesthetic value. Conclusions: tooth extraction and administration of infiltration local anesthesia caused hypotension with no significant effect (p > 0.05) while it caused increase in pulse rate with a significant effect (p < 0.05). Administration of infiltration local anesthesia caused significant effects on salivary chromogranin A levels, also this study showed that there was significant inverse correlation between systolic blood pressure and chromogranin A levels(p < 0.05) after administration of infiltrations local anesthesia during dental treatments (tooth extraction).

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Section: Discussionmentioning

confidence: 96%

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Al-Saffar¹,

Al–Sandook²,

Taha³

2014

AJPS

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“…Complications can be classified into two categories: neurological complications (facial numbness, dental or gum numbness, and tingling sensation) and complications resulting from blood leakage (facial pain, facial swelling, and bruising). Epinephrine hydrochloride is widely used in various nasal surgeries to reduce bleeding during operations [11,12]. There have been no reports of bleeding control of the maxillary sinus mucosa after CFP.…”

Section: Discussionmentioning

confidence: 99%

“…Epinephrine hydrochloride is frequently used in nasal surgery to reduce mucosal bleeding [11,12]. Removal of extensive mucosal disease of the maxillary sinus often results in copious bleeding or diffuse blood oozing from the mucosal surface.…”

Section: Introductionmentioning

confidence: 99%

Effect of maxillary sinus packing with epinephrine hydrochloride-soaked cotton pledgets on complications after canine fossa puncture

Byun

Lee

2013

Acta Oto-Laryngologica

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A total of 57 patients were included. Group 1 underwent 36 CFPs, and complications occurred in 20 sides of 17 patients. Group 2 had 39 CFPs, and 20 patients experienced complications in 26 sides. The total number of complications was 40 and 73 in groups 1 and 2, respectively. Incidence or duration of facial, dental, or gum numbness did not differ between groups. Tingling sensation, facial pain, facial swelling, and bruising showed significantly lower occurrence rates and shorter duration in group 1.

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“…Mechanical dilation [16] and application of adrenaline [17] have also been used to prepare the nasopharyngeal passages and minimise epistaxis during nasotracheal intubation. Use of the Parker Flex-Tip tube for nasotracheal intubation may have advantages over these methods since no other special equipment or preparation is required, except for routine lubrication of the Parker Flex-Tip tube before tracheal intubation.…”

Section: Discussionmentioning

confidence: 99%

The Parker Flex‐Tip™ tube for nasotracheal intubation: the influence on nasal mucosal trauma

et al. 2009

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SummaryWe tested our hypothesis that use of the Parker Flex‐Tip™ tracheal tube could reduce the incidence of nasal mucosal trauma during nasotracheal intubation when compared with a conventional tip tracheal tube. One hundred and two patients, who were scheduled for elective oral surgery in which nasotracheal intubation was indicated to optimise the surgical approach, were recruited into this study. Either a Flex‐Tip tracheal tube or a conventional tip tracheal tube was chosen randomly for each nasotracheal intubation. The incidence of epistaxis using the Flex‐Tip tracheal tube (6 (11.8%)) was significantly lower than that with the conventional tip tracheal tube (18 (35.3%); p = 0.009). Nasal pain due to intubation, rated on a 100‐mm visual analogue scale, was less intense with the Flex‐Tip tracheal tube (median, (10th–90th percentile) 19 (12–28) mm compared with the conventional tip tracheal tube (30 (22–35) mm; p < 0.001). The Flex‐Tip tracheal tube thus appeared to reduce the incidence of nasal mucosal trauma during nasotracheal intubation and the incidence of post‐intubation nasal pain, compared with the conventional tip tracheal tube.

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Effects of Nasal Application of an Epinephrine and Lidocaine Mixture on the Hemodynamics and Nasal Mucosa in Oral and Maxillofacial Surgery

Cited by 24 publications

References 21 publications

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Hemodynamic Effects of Local Anesthesia and its Possible Correlation with Chromogranin A

Effect of maxillary sinus packing with epinephrine hydrochloride-soaked cotton pledgets on complications after canine fossa puncture

The Parker Flex‐Tip™ tube for nasotracheal intubation: the influence on nasal mucosal trauma

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