Effects of pollutants and microplastics ingestion on oxidative stress and monoaminergic activity of seabream brains

Hoyo-Alvarez, Esther; Arechavala-López, Pablo; Jiménez-García, Manuel; Solomando, Antònia; Alomar, Carme; Sureda, Antoni; Moranta, David; Deudero, Salud

doi:10.1016/j.aquatox.2021.106048

Cited by 31 publications

(10 citation statements)

References 90 publications

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“…Similarly, in the present study, GST activity significantly increased in the group with high MP presence, matching the results from both Alomar et al (2017) [20] and Solomando et al (2020) [24], which also reported increased GST activity related to the presence of a larger amount of ingested MPs in M. surmuletus and S. aurata, respectively. Furthermore, increased GST activity was also observed in the livers of M. surmuletus and the brain of B. boops when exposed to microplastics [77], as well as in the brains of S. aurata subjected to an MP-enriched diet [30]. Therefore, plastic presence seems to be closely linked to GST, GRd, and GPx in the case of the studied X. novacula liver samples.…”

Section: Discussionmentioning

confidence: 65%

“…In this sense, oxidative stress and detoxifying biomarkers can be used to assess the potential effects of plastic ingestion on marine wildlife. Solomando et al (2020Solomando et al ( , 2022 [20,29] studied the oxidative stress response to MP ingestion in Sparus aurata gut and Seriola durmilierii liver, respectively, whilst Hoyo-Alvarez et al (2022) [30] studied oxidative stress in seabream brains, reporting the induction of the protective system. Similarly, oxidative stress was also evident in Eriocheir sinensis liver tissue when exposed to MPs [31].…”

Section: Introductionmentioning

confidence: 99%

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Microplastic Presence in the Digestive Tract of Pearly Razorfish Xyrichtys novacula Causes Oxidative Stress in Liver Tissue

Cohen-Sánchez

Solomando

Pinya

et al. 2023

Toxics

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Plastic pollution in the oceans is a growing problem, with negative effects on exposed species and ecosystems. Xyrichtys novacula L. is a very important fish species both culturally and economically in the Balearic Islands. The aim of the present study was to detect and categorise the presence of microplastics (MPs) in the digestive tract of X. novacula, as well as the existence of oxidative stress in the liver. For this purpose, the fish were categorised into two groups based on the number of MPs observed in the digestive tracts: a group with no or low presence of MPs (0–3 items) and a group with a higher presence of MPs (4–28 items). MPs were found in 89% of the specimens analysed, with a dominance of fibre type and blue colour. Regarding the type of polymer, polycarbonate was the most abundant, followed by polypropylene and polyethylene. For the group with a greater presence of MPs, the activities of the antioxidant enzymes glutathione peroxidase and glutathione reductase, as well as the phase II detoxification enzyme glutathione s-transferase, were higher than the activities observed in fish with little to no presence of MPs. The activities of catalase and superoxide dismutase and the levels of malondialdehyde did not show significant differences between both groups. In conclusion, these results demonstrate the presence of MPs in the digestive tract of X. novacula and the existence of an antioxidant and detoxification response, mainly based on the glutathione-based enzymes.

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Section: Discussionmentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

Microplastic Presence in the Digestive Tract of Pearly Razorfish Xyrichtys novacula Causes Oxidative Stress in Liver Tissue

Cohen-Sánchez

Solomando

Pinya

et al. 2023

Toxics

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“…Furthermore, citric acid is useful not only in terrestrial animal studies (Liu et al, 2014), but also in aquatic animals, such as fish, for improving calcium, phosphorus, and zinc intake (Sugiura et al, 1998). Citric acid has been shown to improve the availability of phosphorus in rainbow trout (Pandey and Satoh, 2008), red sea bream (Pagrus major) (Hossain et al, 2007), beluga (Huso huso) (Khajepour and Hosseini, 2012), rohu (Labeo rohita) (Baruah et al, 2007), and yellowtail (Seriola quinqueradiata) (Sarker et al, 2012). Recently, Sayed et al, 2021a andSayed et al, 2022 stated that lycopene, citric acid, and chlorella can be recommended as a feed supplement to improve hemato-biochemical alterations and oxidative damage as well as reproductive impairment induced by MPs toxicity in the African catfish (C. gariepinus).…”

Section: Introductionmentioning

confidence: 99%

Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus)

Hamed

Soliman

Eid

et al. 2022

Front. Environ. Sci.

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A few studies assessed how natural products can protect fish from the neurotoxic effects of Microplastics (MPs). Therefore, the goal of this study was to look into the neurotoxicity of PE-MPs on the brain tissue of African catfish (C. gariepinus), and whether dietary feeding on Chlorella, citric acid, and lycopene could help alleviate their toxicity. Five groups of fish were used: The first group received a standard diet (control). The second group was fed 500 mg/kg PE-MP. The third group was fed PE-MP + lycopene (500 mg/kg diet). The fourth group was fed PE-MP + citric acid (30 g/kg diet). And the fifth group was fed PE-MP + Chlorella (50 g/kg diet) for 15 days. The activities of Acetylcholinesterase (Ach), Monoamine Oxidase (MAO), Aldehyde Oxidase (AO), and Nitric Oxide (NO), and the histological effect on brain tissues were then assessed. The activity of the four neurological biomarker enzymes investigated was altered significantly in fish subjected to PE-MP alone compared with the control group. For fish exposed to PE-MP with lycopene, citric acid, or Chlorella, the activities of these neurological enzymes significantly improved particularly with Chlorella compared with fish fed PE-MP individually. Histological investigations illustrated that being subjected to PE-MPs effected cellular alterations in the telencephalon, including diffuse distorted and degraded neurons, encephalomalacia, aggregated neuroglial cells (gliosis), as well as deformed and necrotic neurons, neuropil vacuolation (spongiosis), aggregated neuroglial cells (gliosis), pyknotic neurons, and shrunken Purkinje cells which were found in the cerebellum. Most histological alterations induced by exposure to PE-MP feeding were restored by dietary feeding on Chlorella, citric acid, and lycopene. Accordingly, this study recommends using citric acid, lycopene, and Chlorella as a natural remedy against MP neurotoxicity particularly with Chlorella.

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“…Due to their small size, MNPs have the potential to affect organisms on a cellular level (Prinz and Korez, 2020;Banerjee and Shelver, 2021). For example, in fish, MNPs lead to formation of reactive oxygen species (ROS) and increased oxidative stress, inducing cellular damage in liver, blood cells, gills, digestive tract, and brain (Pitt et al, 2018b;Hu and Palic, 2020;Buwono et al, 2022;Capóet al, 2022;Hoyo-Alvarez et al, 2022;Rangasamy et al, 2022). In fish, MNPs induced mitochondrial stress, altered hormonal regulation of energy metabolism, and catabolic and anabolic processes, which can limit the ability and flexibility of the organism to respond to future stresses (Brun et al, 2019;Trevisan et al, 2019;Trevisan et al, 2020;Wang et al, 2022).…”

Section: Effects Of Plastics On Animal Healthmentioning

confidence: 99%

A growing crisis for One Health: Impacts of plastic pollution across layers of biological function

et al. 2022

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The global accumulation of plastic waste has reached crisis levels. The diverse and multilayered impacts of plastic on biological health prompts an evaluation of these effects from a One Health perspective, through which the complexity of these processes can be integrated and more clearly understood. Plastic particles ranging from nanometers to meters in size are found throughout every ecosystem on Earth, from the deepest marine trenches to the highest mountains. Plastic waste affects all layers of biological organization, from the molecular and cellular to the organismal, community, and ecosystem-levels. These effects are not only mediated by the physical properties of plastics, but also by the chemical properties of the plastic polymers, the thousands of additives combined with plastics during manufacturing, and the sorbed chemicals and microbes that are transported by the plastic waste. Using a One Health framework we provide an overview of the following themes: 1) ways in which plastic impacts global health across levels of biological organization, 2) how the effects of plastic interact between layers of biology, and 3) what knowledge gaps exist in understanding the effects of plastic within and between biological scales. We also propose potential solutions to address this growing crisis, with an emphasis on One Health perspectives that consider the oneness of animals, humans, and the environment.

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Effects of pollutants and microplastics ingestion on oxidative stress and monoaminergic activity of seabream brains

Cited by 31 publications

References 90 publications

Microplastic Presence in the Digestive Tract of Pearly Razorfish Xyrichtys novacula Causes Oxidative Stress in Liver Tissue

Microplastic Presence in the Digestive Tract of Pearly Razorfish Xyrichtys novacula Causes Oxidative Stress in Liver Tissue

Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus)

A growing crisis for One Health: Impacts of plastic pollution across layers of biological function

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