Effects of polyphenols on skin damage due to ultraviolet A rays: an experimental study on rats

Abstract

These results show a protective effect of EGCG when applied topically before UVA exposure. No benefit was detected when EGCG was applied after UV exposure.

Induction of apoptosis by tea polyphenols mediated through mitochondrial cell death pathway in mouse skin tumors

“…Both black and green tea have shown cancer chemopreventive activities against ultraviolet light, chemically induced and genetic models of carcinogenesis. [8][9][10][11] A study also showed the regression of experimentally established induced skin papillomas on oral administration of green tea. 12 Another work showed, the antitumorigenic effect of BTP in two-stage mouse be 100.60 ± 12 mm 3 /mouse in DMBA treated group II.…”

Natural Ingredients in Cosmetics from Malaysian Plants: A Review

“…In addition, the study depigmenting effects of catechins are shown to promote melanin synthesis inhibition of B16 melanoma (Sato & Toriyama 2009). Polyphenols can also act as photoprotection (Martorana et al 2013;Ruszova et al 2013;Sevin et al 2007) thus allowing the compounds to incorporate in sunscreen formulation as a prevention against ultraviolet (UV) radiation.…”

Photoprotective Effect of Tea and its Extracts against Ultraviolet Radiation-Induced Skin Disorders

“…GTPs protected skin against UV rays and enhanced proliferation of fibroblast cells significantly and had good tyrosinase inhibitory effects [19]. However, the effects of green tea extract depended on the application method [20].…”

“…There was a study showing that the application method of EGCG influenced its photoprotective efficacy. The photoprotective effect of EGCG was observed when it was applied topically before UVA exposure, but no benefit was detected when it was applied after UV exposure [20]. Oral administration of green tea polyphenols (GTP) in drinking water (d.w.) significantly prevented single or multiple UVB irradiation-induced depletion of antioxidant enzymes, oxidative stress, but its photoprotective efficacy was lesser than that of topical treatments of GTP.…”