In this paper, the evolution of creep strain and mechanical properties of 2195 Al-Li alloy is investigated at different temperatures (160/170/180°C), with the aim of discovering the mechanism of temperature influence on creep properties and providing a reference for improving the creep properties of the target material by adjusting the temperature in the future. This study demonstrates that the creep curve is strongly influenced by temperature, with a plateau and a transition period occurring at low temperatures. As the temperature increases, the creep curve gradually reverts to the typical two-stage creep characteristics due to the interaction of dislocation density proliferation and dislocation reversion within the material at high temperatures. In addition, by means of tests such as TEM, it was confirmed that the decrease in mechanical properties of the material caused by increasing the creep temperature is mainly due to the coarsening of precipitates and the appearance of precipitation-free zones at grain boundaries.