Effects of Pre- or Post-Exercise Low-Level Laser Therapy (830 nm) on Skeletal Muscle Fatigue and Biochemical Markers of Recovery in Humans: Double-Blind Placebo-Controlled Trial

Reis, Filipe Abdalla dos; Silva, Baldomero Antonio Kato da; Laraia, Érica Martinho Salvador; Melo, Rhaiza Marques de; Silva, Patrícia Henrique; Leal-Junior, Ernesto César Pinto; Carvalho, Paulo de Tarso Camillo de

doi:10.1089/pho.2013.3617

Cited by 66 publications

(44 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It has been explained in the current study that both 10% EEC and LLLT have similar effects on LDH activity. Previous studies have reported a significant difference in LDH activity as compared to control, placebo, 35 and other interventions. 36 In accordance with this study, serum LDH activity remained elevated 48 hours after muscle damage.…”

Section: Discussionmentioning

confidence: 89%

“…Lavender and Nosaka 4 reported no significant difference in changes in CK activity when compared to control. Another study showed that CK activity is less in 10% EEC group as compared to control, 11 and Dos Reis et al 35 reported that the application of laser before and after exercise reduced the level of CK. Baroni et al 12 found that LLLT provided protection and reduced the level of CK when compared to placebo.…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

Nausheen

Moiz

Raza

et al. 2017

JPR

View full text Add to dashboard Cite

Background/objectivePrevious studies have already reported an independent effect of light-load eccentric exercise (10% eccentric exercise contraction [EEC]) and low-level laser therapy (LLLT) as a protective measure against more strenuous eccentric exercise. However, the difference between these two interventions is largely unknown. Therefore, the present study aimed to compare the preconditioning effect of 10% EEC vs. LLLT on subjective, physiological, and biochemical markers of muscle damage in elbow flexors in collegiate men.MethodsAll 36 enrolled subjects were randomly assigned to either 10% EEC or LLLT group. Subjects in 10% EEC group performed 30 repetitions of an eccentric exercise with 10% maximal voluntary contraction strength 2 days prior to maximal eccentric exercise bout, whereas subjects in LLLT group were given LLLT. All the indirect markers of muscle damage were measured pre-exercise and at 24, 48, and 72 hours after the exercise-induced muscle damage protocol.ResultsThe muscle soreness was reduced in both groups (p = 0.024); however, soreness was attenuated more in LLLT group at 48 hours (33.5 vs. 42.7, p = 0.004). There was no significant difference between the effect of 10% EEC and LLLT groups on other markers of muscle damage like a maximum voluntary isometric contraction (p = 0.47), range of motion (p = 0.16), upper arm circumference (p = 0.70), creatine kinase (p = 0.42), and lactate dehydrogenase (p = 0.08). Within-group analysis showed both interventions provided similar protection over time.ConclusionThis study indicated that light-load eccentric exercise confers similar protective effect against subsequent maximal eccentric exercise as LLLT. Both the treatments could be used reciprocally based on the patient preference, costs, and feasibility of the equipment.

show abstract

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 94%

Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

Nausheen

Moiz

Raza

et al. 2017

JPR

View full text Add to dashboard Cite

show abstract

“…These energy doses are similar to doses emitted by diode lasers in a previous study [24], reinforcing the idea that light is light [37] and there is not a large difference between these light sources to prevent exerciseinduced muscle damage (CK) if the total dose applied per muscle group is adequate. However, it is important to remark that it is possible that the light dose used to prevent muscle damage with LEDT in a pre-conditioning regimen may not be the same dose necessary if the light therapy is applied after the exercise [38]. It is accepted that cells under biochemical or mechanical stress have better responses to light [39] than cells in homeostasis.…”

Section: Discussionmentioning

confidence: 99%

Light-emitting diode therapy (LEDT) before matches prevents increase in creatine kinase with a light dose response in volleyball players

et al. 2015

View full text Add to dashboard Cite

Low-level laser (light) therapy (LLLT) has been applied over skeletal muscles before intense exercise (muscular pre-conditioning) in order to reduce fatigue and muscle damage (measured by creatine kinase, CK) in clinical trials. However, previous exercise protocols do not exactly simulate the real muscle demand required in sports. For this reason, the aim of this randomized and double-blind placebocontrolled trial was to investigate whether light-emitting diode therapy (LEDT) applied over the quadriceps femoris muscles, hamstrings, and triceps surae of volleyball players before official matches could prevent muscle damage (CK) with a dose response, establishing a therapeutic window. A professional male volleyball team (12 athletes) was enrolled in this study, and LEDT was applied before 4 matches during a national championship. LEDT used an array of 200 lightemitting diodes (LEDs) arranged in 25 clusters of 4 infrared LEDs (850±20 nm; 130 mW) and 25 clusters of 4 red LEDs (630±10 nm; 80 mW). Athletes were randomized to receive one of four different total doses over each muscle group in a double-blind protocol: 105 J (20 s), 210 J (40 s), 315 J (60 s), and placebo (no light for 30 s). CK in blood was assessed 1 h before and 24 h after each match. LEDT at 210 J avoided significant increases in CK (+10 %; P=0.993) as well as 315 J (+31 %, P=0.407). Placebo (0 J) allowed a significant increase in CK (+53 %; P=0.012) as well as LEDT at 105 J (+ 59 %; P=0.001). LEDT prevented significant increases of CK in blood in athletes when applied before official matches with a light dose response of 210-315 J, suggesting athletes might consider applying LEDT before competition.

show abstract

“…The latter demonstrated a decrease in the skeletal muscle damage related to the exercise and a delay in muscle fatigue, enhancing skeletal muscle performance in both healthy volunteers and athletes. Moreover, dos Reis et al 15 demonstrated that LLLT either before or after fatigue protocol reduced the concentrations of serum lactate and CK in male soccer players.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, recent systematic reviews demonstrated that LLLT attenuates the muscle's inflammatory mediators and enhances activity of antioxidant enzymes when applied after or before exercise 11 - 13 . Thus, these physiological adaptations could improve muscular performance and decrease fatigue during physical exercise programs 7 , 14 , 15 .…”

Section: Introductionmentioning

confidence: 99%

Effect of low-level laser therapy (808 nm) on skeletal muscle after endurance exercise training in rats

Assis

Yamashita

Magri

et al. 2015

Braz. J. Phys. Ther.

View full text Add to dashboard Cite

| Background: Low-level laser therapy (LLLT) has been demonstrated to be effective in optimizing skeletal muscle performance in animal experiments and in clinical trials. However, little is known about the effects of LLLT on muscle recovery after endurance training. Objective: This study evaluates the effects of low-level laser therapy (LLLT) applied after an endurance training protocol on biochemical markers and morphology of skeletal muscle in rats. Method: Wistar rats were divided into control group (CG), trained group (TG), and trained and laser irradiated group (TLG). The endurance training was performed on a treadmill, 1 h/day, 5 days/wk, for 8 wk at 60% of the maximal speed reached during the maximal effort test (Tmax) and laser irradiation was applied after training. Results: Both trained groups showed significant increase in speed compared to the CG. The TLG demonstrated a significantly reduced lactate level, increased tibialis anterior (TA) fiber cross-section area, and decreased TA fiber density. Myogenin expression was higher in soleus and TA muscles in both trained groups. In addition, LLLT produced myogenin downregulation in the TA muscle of trained animals. Conclusion: These results suggest that LLLT could be an effective therapeutic approach for stimulating recovery during an endurance exercise protocol.Keywords: low-level laser therapy; endurance exercise; lactate; skeletal muscle; myogenin; physical therapy. BULLET POINTS• LLLT applied after an endurance training protocol.• LLLT decreased lactate concentration at rest.• LLLT improved muscle fiber morphology.• LLLT decreased myogenin expression.• LLLT could be an effective therapeutic approach for stimulating recovery. HOW TO CITE THIS ARTICLEAssis L, Yamashita F, Magri AMP, Fernandes KR, Yamauchi L, Renno ACM. Effect of low-level laser therapy (808 nm) on skeletal muscle after endurance exercise training in rats. Braz J Phys Ther. 2015 Nov-Dec; 19(6):457-465. http://dx

show abstract

Effects of Pre- or Post-Exercise Low-Level Laser Therapy (830 nm) on Skeletal Muscle Fatigue and Biochemical Markers of Recovery in Humans: Double-Blind Placebo-Controlled Trial

Abstract: Laser application either before or after fatigue reduced the post-fatigue concentrations of serum lactate and CK. The results were more pronounced in the post-fatigue laser group.

Cited by 66 publications

References 28 publications

Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men

Light-emitting diode therapy (LEDT) before matches prevents increase in creatine kinase with a light dose response in volleyball players

Effect of low-level laser therapy (808 nm) on skeletal muscle after endurance exercise training in rats

Contact Info

Product

Resources

About