Effects of QMix and ethylenediaminetetraacetic acid on decalcification and erosion of root canal dentin

Abstract

The aim of this study was to evaluate the effect of initial NaOCl on the decalcification and erosion ability of EDTA and QMix. Sixty-maxillary-incisors were bisected longitudinally and the tooth-halves were used. The experiment was conducted in two-sets. In set-I, 80-tooth halves were treated in the presence or absence of initial NaOCl and EDTA. In set-II, 40-tooth halves were immersed in NaOCl and QMix. After each treatment, calcium-ion release was determined with flame photometry. The erosion was imaged using SEM. Initial NaOCl led to concentration- and time-dependent increase in calcium removal effect of 17% EDTA (p < .05). The rate of calcium removal and root canal wall erosion was considerably more severe with the use of 5% NaOCl for 3 min (p < .05). QMix as a final solution showed less decalcification and erosion than 17% EDTA when used 5% NaOCl as an initial irrigant (p < .05). Optimizing the concentration and application time of NaOCl can decrease the decalcification effect of chelating agents.

The effect of final irrigation with MTAD, QMix, and EDTA on smear layer removal and mineral content of root canal dentin

“…On the other hand, some studies found that MTAD removes more P (Kumar et al, ) while QMix eliminates more Ca and P from root dentin in comparison to 17% EDTA (Ballal, Jain, & Tay, ). Many of these studies focused on the demineralizing effect of the MTAD (Sayin et al, ) or QMix alone (Aksel et al, ; Kumar et al, ), although under clinical conditions, they are used after initial irrigation with NaOCl. Namely, it has been shown that NaOCl can significantly affect the mineral composition of root dentin (Doğan & Çalt, ) and that changes in the mineral composition of dentine are not the result of the use of chelating agents but the use of NaOCl as an irrigant (Zhang et al, ).…”

“…As calcium chelating agent, 17% EDTA extracts significant amount of Ca from root canal dentin (Sayin, Serper, Cehreli, & Kalayci, 2007). It has been shown that MTAD and QMix were also capable to remove Ca from root canal dentin, but their effect is less pronounced than that of 17% EDTA (Aksel, Serper, Kalayci, Somer, & Erisken, 2016;Yadav, Tikku, Chandra, Yadav, & Patel, 2015). On the other hand, some studies found that MTAD removes more P (Kumar et al, 2016) while QMix eliminates more Ca and P from root dentin in comparison to 17% EDTA (Ballal, Jain, & Tay, 2016).…”

“…On the other hand, some studies found that MTAD removes more P (Kumar et al, 2016) while QMix eliminates more Ca and P from root dentin in comparison to 17% EDTA (Ballal, Jain, & Tay, 2016). Many of these studies focused on the demineralizing effect of the MTAD (Sayin et al, 2009) or QMix alone (Aksel et al, 2016;Kumar et al, 2016), although under clinical conditions, they are used after initial irrigation with NaOCl.…”

Qualitative analysis of smear layer treated with different etidronate concentrations: A scanning electron microscopy study

“…The use of NaOCl in conjunction with EDTA results in the formation of a milky white‐colored precipitate, which has a negative effect on the tissue‐dissolution ability of NaOCl (Grawehr, Sener, Waltimo, & Zehnder, ). Furthermore, EDTA may weaken the dentinal structure and erode the tubular dentine if it remains in the root canal for a prolonged period (Aksel, Serper, Kalayci, Somer, & Erisken, ; Saleh & Ettman, ).…”

Influence of sodium hypochlorite/etidronic acid combination and SmearOFF on push-out bond strength of fiber posts to root dentin

“…EDTA is strong chelating agent and could remove the smear layer 35) ; however, if the root canal has prolonged contact with EDTA, it may weaken the dentin structure 36) and erode the tubular dentin 37) . Without using an oxidizing agent such as NaOCl, the chemical reactions might be limited to between the superficial inorganic layer of the smear-covered dentin and the chelating agents 17,38) .…”