Effects of Recombinant Spidroin rS1/9 on Brain Neural Progenitors After Photothrombosis-Induced Ischemia

Abstract

Effects of Spidroin on Brain Neural Progenitors material for therapeutic usage aimed at enhancing brain plasticity by interacting with stem cell niches. Substances formed from rS1/9 can also be used to enhance primary neuroprotection resulting in reduced cell death in the injury area.

Recombinant Spidroin Microgel as the Base of Cell-Engineered Constructs Mediates Liver Regeneration in Rats

“…The surface elements include nanostructures (diameter of 100 to 300 nm) and microstructures (10 to 30 μm) as well as micropores of 2–70 μm in diameter ( Figure 1 ). These nanostructures facilitate interactions with cells; the great number of pores including nanopores [ 29 ] and the surface positive charge perform the same function.…”

“…Due to the mild conditions of the assembly, it is relatively easy to add various substances and particles to the gels thus bringing them to living cells and obtaining 3D cell constructs for tissue engineering [ 27 ]. In laboratory animals, bioengineered rS1/9-derived microgels have exerted the function of a scaffold for cells but have also influenced the immune response; they have shown pro-regenerative properties as well [ 28 , 29 ].…”